Tocilizumab in SARS-CoV-2 patients with the syndrome of cytokine storm: A narrative review

S Kulanthaivel, VB Kaliberdenko… - Reviews on Recent …, 2021 - ingentaconnect.com
Introduction: Corona virus is a group of viruses that cause diseases in mammals and birds.
In humans, these families of viruses can cause respiratory infections from a mild form to fatal …

Recovery of COVID-19 acute respiratory distress syndrome with tocilizumab: successful outcome in two critically ill patients

JD Cala-García, JD Sierra-Breton… - …, 2020 - Future Medicine
Background: Severe pneumonia and acute respiratory distress syndrome (ARDS) due to
COVID-19 is a challenge for nowadays medical practice. Although there is no clarity in the …

Evaluation of infliximab/tocilizumab versus tocilizumab among COVID-19 patients with cytokine storm syndrome

NM Sarhan, AEA Warda, HSG Ibrahim, MF Schaalan… - Scientific Reports, 2023 - nature.com
Abstract Coronavirus Disease 2019 (COVID-19) continues to spread rapidly. Monoclonal
antibodies as well as anti-tumor necrosis factor are considered promising treatments for …

Modulation of Covid‐19 cytokine storm by tocilizumab

A Boretti, B Banik - Journal of Medical Virology, 2022 - Wiley Online Library
Abstract Coronavirus disease 2019 (Covid‐19) is the illness caused by severe acute
respiratory syndrome coronavirus 2, first identified in Wuhan, China at the end of 2019. On …

[HTML][HTML] Tocilizumab therapy for COVID-19: A comparison of subcutaneous and intravenous therapies

MA Kaminski, S Sunny, K Balabayova, A Kaur… - International Journal of …, 2020 - Elsevier
Background The release of pro-inflammatory cytokines, resulting in cytokine storm
syndrome, contributes to the morbidity and mortality associated with COVID-19 disease. This …

Therapeutic role of tocilizumab in SARS-CoV-2-induced cytokine storm: rationale and current evidence

C Pelaia, C Calabrese, E Garofalo, A Bruni… - International Journal of …, 2021 - mdpi.com
Among patients suffering from coronavirus disease 2019 (COVID-19) syndrome, one of the
worst possible scenarios is represented by the critical lung damage caused by the severe …

Tocilizumab for severe COVID-19 infection and multisystem inflammatory syndrome in adults and children

AN Edinoff, ES Alpaugh, O Newgaard, I Wajid… - Life, 2023 - mdpi.com
Coronavirus disease 2019 (COVID-19) rapidly emerged as a global pandemic, placing
imminent stress and burden on healthcare resources and workers worldwide. Many patients …

The role of tocilizumab in cytokine storm and improving outcomes in COVID-19

A Ali, MH Kamjani… - Recent patents on anti …, 2020 - ingentaconnect.com
To date, severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) has infected
millions of individuals worldwide. This virus causes coronavirus disease 2019 (COVID-19) …

Tocilizumab: a therapeutic option for the treatment of cytokine storm syndrome in COVID-19

A Saha, AR Sharma, M Bhattacharya, G Sharma… - Archives of medical …, 2020 - Elsevier
Presently, we need more therapeutic molecules for this COVID-19 outbreak. The severity
and mortality of the disease is associated with a high level of release of cytokine in the …

Rational use of tocilizumab in the treatment of novel coronavirus pneumonia

S Zhang, L Li, A Shen, Y Chen, Z Qi - Clinical drug investigation, 2020 - Springer
Since December 2019, a novel coronavirus pneumonia (COVID-19) has broken out in
Wuhan, China and spread rapidly. Recent studies have found that⁓ 15.7% of patients …