Alkaline phosphatase is a promising therapeutic agent in the Gram-negative bacterial
lipopolysaccharide (LPS) mediated acute and chronic diseases. Contrary to other alkaline …

Alkaline phosphatase (AP) is a phosphate transferase present in bacteria and eukaryotes. In
previous studies, we have shown that AP is able to dephosphorylate lipopolysaccharide …

Lipopolysaccharide (LPS) is a bacterial endotoxin leading to endotoxemia. Its virulence
factor 'diphosphoryl lipid A'can be abolished by alkaline phosphatase (AP). A novel AP gene …

A complete genomic clone and a full-length cDNA coding for bovine intestinal alkaline
phosphatase have been isolated and sequenced. The gene (5.4 kb) contains 11 exons …

Background The development of any vector system as a gene delivery system requires its
optimization in vitro and in vivo. Preliminary studies frequently involve the use of a reporter …

Background A host defense function for Alkaline phosphatases (ALPs) is suggested by the
contribution of intestinal ALP to detoxifying bacterial lipopolysaccharide (endotoxin) in …

The invention relates to isolated nucleic acids encoding recombinant calf intestinal alkaline
phosphatase. Expression vectors and host cells transformed or transfected with such vectors …

Alkaline phosphatases (ALP) are highly ubiquitous enzymes present in the majority of
animals from bacteria to higher vertebrate. Although their wide distribution in nature has …

Alkaline phosphatases (APs) are a family of cell surface glycoproteins that are expressed in
a variety of tissues. Their physiologcial functions are still unclear. Three different AP genes …

A hybrid heterodimeric alkaline phosphatase expressed in KB cells, consisting of placental
and intestinal (fetal) subunits, was purified by use of two different immunoaffinity columns …