T cell immunity to COVID-19 vaccines

EJ Wherry, DH Barouch - Science, 2022 - science.org
The development of multiple COVID-19 vaccines in record time is a major biomedical
achievement, but mechanistic immune correlates of vaccine protection remain to be …

Vaccine designers take first shots at COVID-19

J Cohen - 2020 - science.org
Vaccine designers take first shots at COVID-19 | Science news careers commentary
Journals Science Science brought to you byGoogle Indexer Log in science science …

Clonal analysis of immunodominance and cross-reactivity of the CD4 T cell response to SARS-CoV-2

JS Low, D Vaqueirinho, F Mele, M Foglierini, J Jerak… - Science, 2021 - science.org
The identification of CD4+ T cell epitopes is instrumental for the design of subunit vaccines
for broad protection against coronaviruses. Here, we demonstrate in COVID-19–recovered …

[HTML][HTML] Boosting immunity to COVID-19 vaccines

JA Juno, AK Wheatley - Nature medicine, 2021 - nature.com
Boosting immunity to COVID-19 vaccines | Nature Medicine Skip to main content Thank you for
visiting nature.com. You are using a browser version with limited support for CSS. To obtain the …

[HTML][HTML] The T cell immune response against SARS-CoV-2

P Moss - Nature immunology, 2022 - nature.com
The adaptive immune response is a major determinant of the clinical outcome after SARS-
CoV-2 infection and underpins vaccine efficacy. T cell responses develop early and …

Immune correlates of protection by mRNA-1273 vaccine against SARS-CoV-2 in nonhuman primates

KS Corbett, MC Nason, B Flach, M Gagne, S O'Connell… - Science, 2021 - science.org
INTRODUCTION Mass vaccination against severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) offers the most efficient public health intervention to control the COVID-19 …

Cross-reactive CD4+ T cells enhance SARS-CoV-2 immune responses upon infection and vaccination

L Loyal, J Braun, L Henze, B Kruse, M Dingeldey… - Science, 2021 - science.org
INTRODUCTION The clinical manifestations of COVID-19 vary from asymptomatic infection
to respiratory failure. Severe disease courses are primarily associated with advanced age …

Vaccine-induced CD8+ T cells are key to protection from SARS-CoV-2

E Antoun, Y Peng, T Dong - Nature Immunology, 2023 - nature.com
Vaccine-induced CD8+ T cells are key to protection from SARS-CoV-2 | Nature Immunology Skip
to main content Thank you for visiting nature.com. You are using a browser version with limited …

Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans

J Mateus, A Grifoni, A Tarke, J Sidney, SI Ramirez… - Science, 2020 - science.org
Many unknowns exist about human immune responses to the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) virus. SARS-CoV-2–reactive CD4+ T cells have …

Avoiding pitfalls in the pursuit of a COVID-19 vaccine

L Peeples - Proceedings of the national academy of …, 2020 - National Acad Sciences
The teams of researchers scrambling to develop a coronavirus disease 2019 (COVID-19)
vaccine clearly face some big challenges, both scientific and logistical. One of the most …