B-type natriuretic peptide limits infarct size in rat isolated hearts via KATP channel opening

SP D'souza, DM Yellon, C Martin… - American Journal …, 2003 - journals.physiology.org
B-type natriuretic peptide (BNP) has been reported to be released from the myocardium
during ischemia. We hypothesized that BNP mediates cardioprotection during ischemia …

B-type natriuretic peptide at early reperfusion limits infarct size in the rat isolated heart

DS Burley, GF Baxter - Basic research in cardiology, 2007 - Springer
Natriuretic peptides are regulatory autacoids in the mammalian myocardium whose
functions, mediated via particulate guanylyl cyclase/cGMP, may include cytoprotection …

Natriuretic peptides and myocardial ischaemia

GF Baxter - Basic research in cardiology, 2004 - Springer
In both experimental and clinical myocardial ischaemia, release of BNP occurs rapidly from
ventricular myocardium, prompting speculation that the early activation of the natriuretic …

Hypoxia induces B-type natriuretic peptide release in cell lines derived from human cardiomyocytes

G Casals, J Ros, A Sionis… - American Journal …, 2009 - journals.physiology.org
B-type natriuretic peptide (BNP) is a peptide hormone of myocardial origin with significant
cardioprotective properties. Patients with myocardial ischemia present with high levels of …

Atrial natriuretic peptide administered just prior to reperfusion limits infarction in rabbit hearts

XM Yang, S Philipp, JM Downey, MV Cohen - Basic research in cardiology, 2006 - Springer
We investigated whether atrial natriuretic peptide (ANP) given just prior to reperfusion
reduces infarction in rabbit hearts and whether protection is related to activation of protein …

Rapid ventricular induction of brain natriuretic peptide gene expression in experimental acute myocardial infarction

N Hama, H Itoh, G Shirakami, O Nakagawa, S Suga… - Circulation, 1995 - Am Heart Assoc
Background We have demonstrated that brain natriuretic peptide (BNP) is a cardiac
hormone predominantly synthesized in and secreted from the ventricle. We have also …

Acute changes in circulating natriuretic peptide levels in relation to myocardial ischemia

MS Sabatine, DA Morrow, JA De Lemos… - Journal of the American …, 2004 - jacc.org
Objectives: The aim of this study was to determine the effect of transient myocardial ischemia
on circulating natriuretic peptide levels. Background: Natriuretic peptides are released by …

B-type natriuretic peptide infusions in acute myocardial infarction

RJ Hillock, CM Frampton, TG Yandle, RW Troughton… - Heart, 2008 - heart.bmj.com
Background: Natriuretic peptides have actions likely to ameliorate cardiac dysfunction. B-
type natriuretic peptide (BNP) is indicated as treatment for decompensated cardiac failure …

Coronary vasodilator effects of BNP: mechanisms of action in coronary conductance and resistance arteries

C Zellner, AA Protter, E Ko… - American Journal …, 1999 - journals.physiology.org
Brain natriuretic peptide (BNP), a hormone secreted predominantly in ventricular myocytes,
may influence coronary vascular tone. We studied the coronary vasodilatory response to …

Atrial natriuretic peptide protects against ischemia-reperfusion injury in the isolated rat heart

K Sangawa, K Nakanishi, K Ishino, M Inoue… - The Annals of thoracic …, 2004 - Elsevier
BACKGROUND: Atrial natriuretic peptide (ANP), a stimulator of particulate guanylate
cyclase, has been found to protect against reoxygenation-induced hypercontracture in …