Prenatal ethanol exposure disrupts intraneocortical circuitry, cortical gene expression, and behavior in a mouse model of FASD

H El Shawa, CW Abbott, KJ Huffman - Journal of Neuroscience, 2013 - Soc Neuroscience
In utero ethanol exposure from a mother9s consumption of alcoholic beverages impacts
brain and cognitive development, creating a range of deficits in the child (Levitt, 1998; Lebel …

The impact of prenatal ethanol exposure on neuroanatomical and behavioral development in mice

CW Abbott, OO Kozanian, J Kanaan… - Alcoholism: Clinical …, 2016 - Wiley Online Library
Background In utero alcohol, or ethanol (EtOH), exposure produces developmental
abnormalities in the brain of the fetus, which can result in lifelong behavioral abnormalities …

Prenatal ethanol exposure and neocortical development: a transgenerational model of FASD

CW Abbott, DJ Rohac, RT Bottom, S Patadia… - Cerebral …, 2018 - academic.oup.com
Abstract Fetal Alcohol Spectrum Disorders, or FASD, represent a range of adverse
developmental conditions caused by prenatal ethanol exposure (PrEE) from maternal …

Binge-like prenatal ethanol exposure causes impaired cellular differentiation in the embryonic forebrain and synaptic and behavioral defects in adult mice

S Subbanna, BS Basavarajappa - Brain Sciences, 2022 - mdpi.com
An embryo's in-utero exposure to ethanol due to a mother's alcohol drinking results in a
range of deficits in the child that are collectively termed fetal alcohol spectrum disorders …

Distinct neurobehavioral dysfunction based on the timing of developmental binge-like alcohol exposure

B Sadrian, M Lopez-Guzman, DA Wilson, M Saito - Neuroscience, 2014 - Elsevier
Gestational exposure to alcohol can result in long-lasting behavioral deficiencies generally
described as fetal alcohol spectrum disorder (FASD). FASD-modeled rodent studies of acute …

The impact of paternal alcohol consumption on offspring brain and behavioral development

KE Conner, RT Bottom… - Alcoholism: Clinical and …, 2020 - Wiley Online Library
Background Fetal alcohol spectrum disorders (FASD) describe the wide array of long‐
lasting developmental abnormalities in offspring due to prenatal alcohol (ethanol [EtOH]) …

Developmental ethanol exposure alters the morphology of mouse prefrontal neurons in a layer-specific manner

EL Louth, HD Luctkar, KA Heney, CDC Bailey - Brain research, 2018 - Elsevier
Chronic developmental exposure to ethanol can lead to a wide variety of teratogenic effects,
which in humans are known as fetal alcohol spectrum disorders (FASD). Individuals affected …

Long-term alterations to the brain transcriptome in a maternal voluntary consumption model of fetal alcohol spectrum disorders

ML Kleiber, BI Laufer, E Wright, EJ Diehl, SM Singh - Brain research, 2012 - Elsevier
Many women continue to consume low to moderate quantities of alcohol during pregnancy,
which can result in the variable neurobehavioural effects in the absence of physiological …

Prenatal ethanol exposure leads to attention deficits in both male and female rats

R Wang, CD Martin, AL Lei, KA Hausknecht… - Frontiers in …, 2020 - frontiersin.org
Background Prenatal ethanol exposure (PE) causes multiple behavioral and cognitive
deficits, collectively referred to as fetal alcohol spectrum disorders (FASD). Studies show that …

Molecular changes during neurodevelopment following second-trimester binge ethanol exposure in a mouse model of fetal alcohol spectrum disorder: from immediate …

K Mantha, BI Laufer, SM Singh - Developmental neuroscience, 2014 - karger.com
Fetal alcohol spectrum disorder (FASD) is an umbrella term that refers to a wide range of
behavioral and cognitive deficits resulting from prenatal alcohol exposure. It involves …