CpG-oligodeoxynucleotides enhance porcine immunity to Toxoplasma gondii

H Kringel, JP Dubey, E Beshah, R Hecker… - Veterinary …, 2004 - Elsevier
Protection against a challenge infection with Toxoplasma gondii VEG strain oocysts was
examined in pigs after vaccination with T. gondii RH strain tachyzoites with or without a …

Protective Effect of Vaccination with Toxoplasma Lysate Antigen and CpG as an Adjuvant against Toxoplasma gondii in Susceptible C57BL/6 Mice

M El‐Malky, L Shaohong, T Kumagai… - Microbiology and …, 2005 - Wiley Online Library
Infection with the intracellular protozoan parasite Toxoplasma gondii causes serious public
health problems to both humans and livestock and of great economic impact worldwide …

Combination of CpG-oligodeoxynucleotides with recombinant ROP2 or GRA4 proteins induces protective immunity against Toxoplasma gondii infection

VR Sánchez, MN Pitkowski, AVF Cuppari… - Experimental …, 2011 - Elsevier
Synthetic oligodeoxynucleotides containing unmethylated CpG motifs (CpG-ODN) have
been characterized as Th1-promoting immunopotentiators, an adjuvant activity desirable for …

Vaccination with Toxoplasma lysate antigen and CpG oligodeoxynucleotides: comparison of immune responses in intranasal versus intramuscular administrations

MA El-Malky, SA Al-Harthi, RT Mohamed… - Parasitology …, 2014 - Springer
Toxoplasma gondii (T. gondii) is one of the most successful intracellular protozoan parasites
on earth and highly prevalent in most warm-blooded vertebrates. There are no drugs that …

Immunological response of sheep to injections of plasmids encoding Toxoplasma gondii SAG1 and ROP1 genes

B Li, G Oledzka, RG McFarlane… - Parasite …, 2010 - Wiley Online Library
Infection with the intracellular protozoan parasite Toxoplasma gondii (T. gondii) causes
health problems to both humans and livestock and has a large economic impact worldwide …

CpG‐containing ODN has a limited role in the protection against Toxoplasma gondii

R Saavedra, R Leyva, EP Tenorio… - Parasite …, 2004 - Wiley Online Library
Bacterial DNA containing immunostimulatory motifs (CpG) induces the development of a
TH1 immune response. Since protection against Toxoplasma gondii is correlated with this …

Partial protection against tissue cysts formation in pigs vaccinated with crude rhoptry proteins of Toxoplasma gondii

JL Garcia, SM Gennari, IT Navarro, RZ Machado… - Veterinary …, 2005 - Elsevier
A vaccine containing crude Toxoplasma gondii rhoptry proteins incorporated in the
immunostimulating complexes (ISCOM) adjuvant was tested in pigs for protecting against …

Protective immunity induced by CpG ODN‐adjuvanted virus‐like particles containing Toxoplasma gondii proteins

HJ Kang, KB Chu, MJ Kim, SH Lee, H Park… - Parasite …, 2021 - Wiley Online Library
Abstract Aims To date, a Toxoplasma gondii vaccine for clinical use remains unavailable,
though multiple vaccine candidates have been suggested. In our previous studies …

An enhanced GRA1–GRA7 cocktail DNA vaccine primes anti-Toxoplasma immune responses in pigs

E Jongert, V Melkebeek, S De Craeye, J Dewit… - Vaccine, 2008 - Elsevier
The protozoan parasite Toxoplasma gondii is the causative agent of a worldwide zoonosis
and high prevalencies can be found both in animals and humans. An important source of …

Adjuvant Effects of Bacillus Calmette–Guerin DNA or CpG‐oligonucleotide in the Immune Response to Taenia solium Cysticercosis Vaccine in Porcine

YJ Guo, D Wu, KY Wang, SH Sun - Scandinavian journal of …, 2007 - Wiley Online Library
The immune stimulation properties of CpG‐oligonucleotides (CpG‐ODN) containing a
central unmethylated CpG motif could be useful for vaccination against parasite infection …