Cytokines from bench to bedside: A retrospective study identifies a definite panel of biomarkers to early assess the risk of negative outcome in COVID-19 patients

M Fabris, F Del Ben, E Sozio, AP Beltrami… - International Journal of …, 2022 - mdpi.com
The main aim of this study was to identify the most relevant cytokines which, when assessed
in the earliest stages from hospital admission, may help to select COVID-19 patients with …

The Role of Inflammatory Cytokines (Interleukin-1 and Interleukin-6) as a Potential Biomarker in the Different Stages of COVID-19 (Mild, Severe, and Critical)

M Ghofrani Nezhad, G Jami, O Kooshkaki… - Journal of Interferon & …, 2023 - liebertpub.com
Cytokine storm refers to the overproduction of immune and inflammatory cells and their
proteins (cytokines)[interleukin (IL)-1 and IL-6] causing acute respiratory distress syndrome …

Unveiling COVID-19 secrets: Harnessing Cytokines as powerful biomarkers for diagnosis and predicting severity

B Wolszczak-Biedrzycka, J Dorf… - Journal of …, 2023 - Taylor & Francis
Introduction In coronavirus disease (COVID-19), inflammation takes center stage, with a
cascade of cytokines released, contributing to both inflammation and lung damage. The …

The role of biomarkers in diagnosis of COVID-19–A systematic review

M Kermali, RK Khalsa, K Pillai, Z Ismail, A Harky - Life sciences, 2020 - Elsevier
Aims As of the 28th April 2020, the COVID-19 pandemic has infiltrated over 200 countries
and affected over three million confirmed people. We review different biomarkers to evaluate …

Inflammatory biomarkers associated with in-hospital mortality in critical COVID-19 patients

K Pál, AA Molnar, A Huțanu, J Szederjesi… - International Journal of …, 2022 - mdpi.com
The COVID-19 pandemic poses global healthcare challenges due to its unpredictable
clinical course. The aim of this study is to identify inflammatory biomarkers and other routine …

Cytokine signature associated with disease severity in COVID-19

J Guo, S Wang, H Xia, D Shi, Y Chen, S Zheng… - Frontiers in …, 2021 - frontiersin.org
Coronavirus disease 2019 (COVID-19) broke out and then became a global epidemic at the
end of 2019. With the increasing number of deaths, early identification of disease severity …

A meta-analysis of potential biomarkers associated with severity of coronavirus disease 2019 (COVID-19)

C Danwang, FT Endomba, JR Nkeck, DLA Wouna… - Biomarker …, 2020 - Springer
Background Prognostic factors for the Coronavirus disease 2019 (COVID1–9) are not well
established. This study aimed to summarize the available data on the association between …

Profiling serum cytokines in COVID-19 patients reveals IL-6 and IL-10 are disease severity predictors

H Han, Q Ma, C Li, R Liu, L Zhao, W Wang… - Emerging microbes & …, 2020 - Taylor & Francis
Since the outbreak of coronavirus disease 2019 (COVID-19) in Wuhan, China, it has rapidly
spread across many other countries. While the majority of patients were considered mild …

A vicious cycle: in severe and critically Ill COVID-19 patients

P Huang, Q Zuo, Y Li, PK Oduro, F Tan… - Frontiers in …, 2022 - frontiersin.org
The coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) virus, is one of the fastest-evolving viral diseases …

Cytokine storm may not be the chief culprit for the deterioration of COVID-19

Y Gao, C Wang, K Kang, Y Peng, Y Luo, H Liu… - Viral …, 2021 - liebertpub.com
COVID-19 is spreading and ravaging all over the world, and the number of deaths is
increasing day by day without downward trend. However, there is limited knowledge of …