Cytokine storm and histopathological findings in 60 cases of COVID-19-related death: from viral load research to immunohistochemical quantification of major players …

P Frisoni, M Neri, S D'Errico, L Alfieri… - … Science, Medicine and …, 2022 - Springer
This study involves the histological analysis of samples taken during autopsies in cases of
COVID-19 related death to evaluate the inflammatory cytokine response and the tissue …

The spectrum of pathological findings in coronavirus disease (COVID-19) and the pathogenesis of SARS-CoV-2

RF Barth, LM Buja, AV Parwani - Diagnostic Pathology, 2020 - Springer
The coronavirus disease (COVID-19) is now a worldwide pandemic and is the most
significant global health crisis of our time. COVID-19 disease continues to present us with …

Pathological changes in the lungs and lymphatic organs of 12 COVID-19 autopsy cases

Q Liu, Y Shi, J Cai, Y Duan, R Wang… - National Science …, 2020 - academic.oup.com
Systematic autopsy and comprehensive pathological analyses of COVID-19 decedents
should provide insights into the disease characteristics and facilitate the development of …

Postmortem examination of three SARS-CoV-2-positive autopsies including histopathologic and immunohistochemical analysis

GC Oprinca, LA Muja - International Journal of Legal Medicine, 2021 - Springer
This paper describes three autopsy cases with postmortem diagnosis of SARS-CoV-2
infection, with detailed macroscopic examination as well as advanced microscopic studies of …

Cytokines and their relationship with the severity and prognosis of coronavirus disease 2019 (COVID-19): a retrospective cohort study

QQ Liu, A Cheng, Y Wang, H Li, L Hu, X Zhao… - BMJ open, 2020 - bmjopen.bmj.com
Objective To delineate the characteristics and clinical significance of plasma inflammatory
cytokines altered in COVID-19. Design Retrospective, single-centre cohort study. Setting …

The immunopathological and histological landscape of COVID-19-mediated lung injury

G Zarrilli, V Angerilli, G Businello, M Sbaraglia… - International Journal of …, 2021 - mdpi.com
A complete understanding of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) physiopathology and related histopathologic lesions is necessary to improve treatment …

Comparison of clinical, para-clinical and laboratory findings in survived and deceased patients with COVID-19: diagnostic role of inflammatory indications in …

M Rokni, K Ahmadikia, S Asghari, S Mashaei… - BMC Infectious …, 2020 - Springer
Abstract Background Since December 2019, when a cluster of pneumonia cases due to
SARS-CoV-2 initially emerged in Wuhan city and then rapidly spread throughout the world …

Profiling serum cytokines in COVID-19 patients reveals IL-6 and IL-10 are disease severity predictors

H Han, Q Ma, C Li, R Liu, L Zhao, W Wang… - Emerging microbes & …, 2020 - Taylor & Francis
Since the outbreak of coronavirus disease 2019 (COVID-19) in Wuhan, China, it has rapidly
spread across many other countries. While the majority of patients were considered mild …

Autopsy findings in COVID-19-related deaths: a literature review

A Maiese, AC Manetti, R La Russa, M Di Paolo… - … Science, Medicine and …, 2021 - Springer
Although many clinical reports have been published, little is known about the pathological
post-mortem findings from people who have died of the novel coronavirus disease. The …

Specific cytokines in the inflammatory cytokine storm of patients with COVID-19-associated acute respiratory distress syndrome and extrapulmonary multiple-organ …

J Wang, X Yang, Y Li, J Huang, J Jiang, N Su - Virology journal, 2021 - Springer
Background To date, specific cytokines associated with development of acute respiratory
distress syndrome (ARDS) and extrapulmonary multiple organ dysfunction (MOD) in COVID …