Ultrasound enhancement of liposome-mediated cell transfection is caused by cavitation effects

S Koch, P Pohl, U Cobet, NG Rainov - Ultrasound in medicine & biology, 2000 - Elsevier
Cationic liposomes (CL) are widely used vectors for gene transfer. Recently, ultrasound (US)
was reported to enhance liposome-mediated gene transfer to eucaryotic cells in culture. The …

[HTML][HTML] Ultrasound enhances liposome-mediated gene transfection

LB Feril Jr, R Ogawa, H Kobayashi, H Kikuchi… - Ultrasonics …, 2005 - Elsevier
Previous studies have shown that some series of liposomes, usually containing cationic
lipids, are useful tools for gene introduction into cells. To investigate the effect of ultrasound …

Tumor specific ultrasound enhanced gene transfer in vivo with novel liposomal bubbles

R Suzuki, T Takizawa, Y Negishi, N Utoguchi… - Journal of controlled …, 2008 - Elsevier
Bubble liposomes (liposomes which entrap an ultrasound imaging gas) may constitute a
unique system for delivering various molecules efficiently into mammalian cells in vitro. In …

Ultrasound enhances gene expression of liposomal transfection

EC UNGER, TP McCREERY… - Investigative …, 1997 - journals.lww.com
RATIONALE AND OBJECTIVES Cationic liposomes are under development as delivery
agents for gene therapy. The authors studied the effect of ultrasound on gene expression in …

Transfection effect of microbubbles on cells in superposed ultrasound waves and behavior of cavitation bubble

T Kodama, Y Tomita, K Koshiyama… - Ultrasound in medicine & …, 2006 - Elsevier
The combination of ultrasound and ultrasound contrast agents (UCAs) is able to induce
transient membrane permeability leading to direct delivery of exogenous molecules into …

Evaluation of the temporal window for drug delivery following ultrasound-mediated membrane permeability enhancement

A Yudina, M Lepetit-Coiffé, CTW Moonen - Molecular imaging and biology, 2011 - Springer
Purpose Ultrasound-induced cavitation facilitates cellular uptake of drugs via increased
membrane permeability. Here, the purpose was to evaluate the duration of enhanced …

The effects of albumin-coated microbubbles in DNA delivery mediated by therapeutic ultrasound

M Duvshani-Eshet, D Adam, M Machluf - Journal of controlled release, 2006 - Elsevier
The application of therapeutic ultrasound (TUS) in combination with contrast agents (USCA)
to mediate gene delivery relies on the understanding of the bioeffects involved. The …

Ultrasound-mediated gene delivery: influence of contrast agent on transfection

S Mehier-Humbert, F Yan, P Frinking… - Bioconjugate …, 2007 - ACS Publications
MAT B III cells were insonified at ultrasound frequencies of 1.15 and 2.25 MHz in the
presence of different ultrasound contrast agents (UCA) and a plasmid encoding for the …

Ultrasound-induced cell membrane porosity

CX Deng, F Sieling, H Pan, J Cui - Ultrasound in medicine & biology, 2004 - Elsevier
Recent studies of ultrasound (US) methods for targeted drug delivery and nonviral gene
transfection revealed new, advantageous possibilities. These studies utilized US contrast …

Physical parameters affecting ultrasound/microbubble-mediated gene delivery efficiency in vitro

A Rahim, SL Taylor, NL Bush, GR Ter Haar… - Ultrasound in medicine …, 2006 - Elsevier
Ultrasound (US)/microbubble-mediated gene delivery is a technology with many potential
advantages suited to clinical application. Previous studies have demonstrated transfection …