The ability to generate multi-omics data coupled with deeply characterizing the clinical
phenotype of individual patients promises to improve understanding of complex …

Network medicine can advance current medical practice by arising as response to the
limitations of a reductionist approach focusing on cardiovascular (CV) diseases as a direct …

Deciphering the molecular basis of human cardiovascular dise... : Current Opinion in
Cardiology Deciphering the molecular basis of human cardiovascular disease through network …

Cardiovascular diseases (CVD) are the leading cause of death worldwide and display
complex phenotypic heterogeneity caused by many convergent processes, including …

The molecular pathways that govern human disease consist of molecular circuits that
coalesce into complex, overlapping networks. These network pathways are presumably …

Cardiovascular diseases (CVD) are diverse disorders affecting the heart and vasculature in
millions of people worldwide. Like other fields, CVD research has benefitted from the deluge …

Network medicine is an emerging area of research dealing with molecular and genetic
interactions, network biomarkers of disease, and therapeutic target discovery. Large-scale …

Cardiovascular diseases are the leading cause of death around the world. Despite the
larger number of genes and loci identified, the precise mechanisms by which these genes …

Complex disease definitions often represent descriptive umbrella terms of symptoms rather
than mechanistic entities. A new study shows how network-based approaches can help …

The past decade has witnessed exponential growth in the generation of high-throughput
human data across almost all known dimensions of biological systems. The discipline of …