Cell replacement therapy has been proposed as a means of replacing specific populations
of cells lost through trauma, disease or ageing. Parkinson's disease is a progressive …

Treating neurodegenerative diseases with cell transplantation has been within reach since
the first pioneering clinical trials in which dopamine neuron progenitors from the fetal brain …

The rationale behind the use of cells as therapeutic modalities for neurodegenerative
diseases in general, and in Parkinson's disease (PD) in particular, is that they will improve …

Current approaches to cell replacement therapy in Parkinson's disease are strongly focused
on the dopamine system, with the view that restoring dopaminergic inputs in a localized and …

“Regenerative medicine” may hopefully provide some relief or therapy for diseases which
we can currently not or only barely treat. This is also true for most diseases presenting with …

Motor dysfunctions in Parkinson's disease are considered to be primarily due to the
degeneration of dopaminergic neurons in the substantia nigra pars compacta …

Current findings suggest that multipotent stem cells may be suitable for cell replacement
therapies in the treatment of neurodegenerative disorders. Embryonic stem (ES) cells are …

The clinical trials with intrastriatal transplantation of human fetal mesencephalic tissue, rich
in dopaminergic neurons, in Parkinson's disease (PD) patients show that cell replacement …

Parkinson's disease (PD) is a progressive neurodegenerative disorder in which the
degeneration of dopaminergic neurons projecting from the substantia nigra to the striatum is …

The use of stem cells in cell replacement therapy for neurodegenerative diseases has
received a great deal of scientific and public interest in recent years. This is due to the …