Abstract Background Wilms Tumor (WT) can occur in association with tumor predisposition
syndromes and/or with clinical malformations. These associations have not been fully …

Abstract Wilms' tumor (WT), the most common childhood kidney cancer, develops in
association with an underlying germline predisposition in up to 15% of cases. Germline …

Wilms tumour has been reported in association with over 50 different clinical conditions and
several abnormal constitutional karyotypes. Conclusive evidence of an increased risk of …

INTRODUCTION: In 9–17% of Wilms tumour patients a predisposing syndrome is present, in
particular WT1-associated syndromes and overgrowth syndromes. Constitutional WT1 …

We report here 24 new Wilms tumor (WT) patients with germline WT1 alterations and a
synopsis of our own previously described and literature cases in whom age of tumor‐onset …

Wilms tumor is responsible for 5% of pediatric malignant tumors or approximately 500 new
cases each year in the United States, with equivalent frequency in boys and girls. The …

Somatic defects at five loci, WT1, CTNNB1, WTX, TP53 and the imprinted 11p15 region, are
implicated in Wilms tumor, the commonest childhood kidney cancer. In this study we …

Predisposing syndromes associated with an increased risk of Wilms tumor (WT) are
responsible for 9–17% of all cases of the malignancy. Due to an earlier age at WT diagnosis …

Clinicians have long recognized the syndromic association between Wilms tumor and a
variety of genetic disorders. The recent identification of molecular mechanisms associated …

Wilms' tumor (WT) is a heterogeneous neoplasia characterized by a number of genetic
abnormalities, involving tumor suppressor genes, oncogenes and genes related to the Wnt …