Altered resting state networks in mild cognitive impairment and mild Alzheimer's disease: an fMRI study

SARB Rombouts, F Barkhof, R Goekoop… - Human brain …, 2005 - Wiley Online Library
Activity and reactivity of the default mode network in the brain was studied using functional
magnetic resonance imaging (fMRI) in 28 nondemented individuals with mild cognitive …

Default-mode network activity distinguishes Alzheimer's disease from healthy aging: evidence from functional MRI

MD Greicius, G Srivastava… - Proceedings of the …, 2004 - National Acad Sciences
Recent functional imaging studies have revealed coactivation in a distributed network of
cortical regions that characterizes the resting state, or default mode, of the human brain …

Resting state fMRI in Alzheimer's disease: beyond the default mode network

F Agosta, M Pievani, C Geroldi, M Copetti… - Neurobiology of …, 2012 - Elsevier
Using resting state (RS) functional magnetic resonance imaging (fMRI), the connectivity
patterns of the default mode (DMN), frontoparietal, executive, and salience networks were …

Functional MRI assessment of task‐induced deactivation of the default mode network in Alzheimer's disease and at‐risk older individuals

M Pihlajamäki, RA Sperling - Behavioural neurology, 2009 - Wiley Online Library
Alzheimer's disease (AD) is the most common form of dementia in old age, and is
characterized by prominent impairment of episodic memory. Recent functional imaging …

Age effect on the default mode network, inner thoughts, and cognitive abilities

K Mevel, B Landeau, M Fouquet, R La Joie… - Neurobiology of …, 2013 - Elsevier
Age-related effects on the default mode network (DMN) connectivity as measured at rest
using functional magnetic resonance imaging (fMRI) are now well described. Little is known …

Aberrant default mode network in subjects with amnestic mild cognitive impairment using resting-state functional MRI

M Jin, VS Pelak, D Cordes - Magnetic resonance imaging, 2012 - Elsevier
Amnestic mild cognitive impairment (aMCI) is a syndrome associated with faster memory
decline than normal aging and frequently represents the prodromal phase of Alzheimer's …

The default mode network in healthy aging and Alzheimer′ s disease

K Mevel, G Chételat, F Eustache… - International journal of …, 2011 - Wiley Online Library
In the past decade, a “default mode network”(DMN) has been highlighted in neuroimaging
studies as a set of brain regions showing increased activity in task‐free state compared to …

Default-mode network activity distinguishes amnestic type mild cognitive impairment from healthy aging: a combined structural and resting-state functional MRI study

F Bai, Z Zhang, H Yu, Y Shi, Y Yuan, W Zhu, X Zhang… - Neuroscience …, 2008 - Elsevier
Resting-state functional magnetic resonance imaging (MRI), have revealed coactivation in a
distributed network that characterizes the default-mode in the human brain. However, details …

Detection of PCC functional connectivity characteristics in resting-state fMRI in mild Alzheimer's disease

HY Zhang, SJ Wang, J Xing, B Liu, ZL Ma… - Behavioural brain …, 2009 - Elsevier
Resting-state networks dissociate in the early stage of Alzheimer's disease (AD). The
posterior cingulate cortex (PCC) in AD brain is vulnerable to isolation from the rest of brain …

Alzheimer's disease and amnestic mild cognitive impairment weaken connections within the default-mode network: a multi-modal imaging study

DC Zhu, S Majumdar, IO Korolev… - Journal of …, 2013 - content.iospress.com
We applied a multi-modal imaging approach to examine structural and functional alterations
in the default-mode network (DMN) that are associated with Alzheimer's disease (AD) and …