Possible reactivating and sensitizing action of neuromyally acting agents

AG Karczmar, K Koketsu, S Soeda - International Journal of …, 1968 - Elsevier
The effects of a bisquaternary oxamide, methoxyambenonium (Meamb), d-tubocurarine (d-
tbc), and of an oxime, pyridine-2-aldoxime methiodide (P-2-AM), upon the frog neuromyal …

Effects of anticholinesterases and of sodium fluoride on neuromyal desensitization

T Akasu, AG Karczmar - Neuropharmacology, 1980 - Elsevier
Desensitization of amphibian neuromyal junction was obtained by either repetitive, brief (2
msec) iontophoretic pulses of acetylcholine (ACh) or by a prolonged (40 sec) iontophoretic …

[PDF][PDF] Interaction between facilitating and depolarizing drugs at the neuromyal junction of the cat

LC Blaber, AG Karczmar - Journal of Pharmacology and Experimental …, 1967 - Citeseer
ABSTRACT BLABER, LC AND AG KARCZMAR: Interaction between facilitating and
depolarizing drugs at the neuromyal junction of the cat. J. Pharmac. exp. Ther. 156: 55-62 …

Adaptation of the neuromuscular junction to constant concentration of ACh

KC Kim, AG Karczmar - International Journal of Neuropharmacology, 1967 - Elsevier
Abstract Effects of prolonged exposure of frog nerve-sartorius muscle preparations to
acetylcholine and certain other agents were studied in relation to phenomena of recovery …

Neuromyopharmacology as related to anticholinesterase action

AG Karczmar, Y Ohta - Fundamental and Applied Toxicology, 1981 - Elsevier
Skeletal neuromyal (NM) junction is one of the primary targets of either acute or chronic
action of anticholinesterases (antiChE's) generally and of organophosphorus (OP) ChE …

Differential effects of the anticonvulsants phenobarbital, ethosuximide and carbamazepine on neuromuscular transmission.

MT Alderdice, BA Trommer - Journal of Pharmacology and Experimental …, 1980 - ASPET
The actions of the anticonvulsants phenobarbital, ethosuximide and carbamazepine were
examined electrophysiologically at the frog neuromuscular junction. Phenobarbital reduced …

[PDF][PDF] Carbamazepine suppression of post-tetanic potentiation at the neuromuscular junction.

N Hershkowitz, KL Dretchen, A Raines - Journal of Pharmacology and …, 1978 - Citeseer
The effects of carbamazepine(CBZ) on posttetanic potentiation(PTP) were evaluated using
an in vivo cat coleus neuromuscular preparation. CBZ was administered ip and plasma CBZ …

Facilitation of neuromuscular transmission by anticholinesterase drugs

LC Blaber - British Journal of Pharmacology and …, 1963 - Wiley Online Library
A close correlation has been shown to exist between the in vitro anticholinesterase
potencies of ambenonium, neostigmine, methoxyambenonium and edrophonium chloride …

Introduction to the session on modulators

AG Karczmar - Neuropharmacology, 1987 - Elsevier
It is difficult to assign the first formulation of the concept of modulation to any particular
investigator or group of investigators. Certain aspects of this concept were raised, without …

Effects of obidoxime chloride on native and sarin-poisoned frog neuromuscular junctions.

CG Caratsch, PG Waser - Pflugers Archiv: European Journal of …, 1984 - europepmc.org
The effect of the oxime reactivator obidoxime chloride (obidoxime) on single frog
neuromuscular junctions has been studied in order to clarify its action on the acetylcholine …