Targeting oxidative stress as a therapeutic approach for idiopathic pulmonary fibrosis

C Estornut, J Milara, MA Bayarri, N Belhadj… - Frontiers in …, 2022 - frontiersin.org
Idiopathic pulmonary fibrosis (IPF) is a chronic interstitial lung disease characterized by an
abnormal reepithelialisation, an excessive tissue remodelling and a progressive fibrosis …

Evaluation of oxidative stress biomarkers in idiopathic pulmonary fibrosis and therapeutic applications: a systematic review

AG Fois, P Paliogiannis, S Sotgia, AA Mangoni… - Respiratory …, 2018 - Springer
Introduction Idiopathic pulmonary fibrosis (IPF), a fatal lung disease of unknown origin, is
characterized by chronic and progressive fibrosing interstitial pneumonia which …

Oxidant–antioxidant imbalance as a potential contributor to the progression of human pulmonary fibrosis

VL Kinnula, M Myllärniemi - Antioxidants & redox signaling, 2008 - liebertpub.com
Idiopathic pulmonary fibrosis (IPF) is the most common idiopathic interstitial pneumonia. IPF
is a disease with poor prognosis and an aggressive nature, and poses major challenges to …

Oxidative stress in pulmonary fibrosis

E Otoupalova, S Smith, G Cheng… - Comprehensive …, 2011 - Wiley Online Library
Oxidative stress has been linked to various disease states as well as physiological aging.
The lungs are uniquely exposed to a highly oxidizing environment and have evolved several …

Oxidative stress, extracellular matrix targets, and idiopathic pulmonary fibrosis

CR Kliment, TD Oury - Free Radical Biology and Medicine, 2010 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is an interstitial lung disease characterized by
progressive fibrosis of the alveolar interstitium. The pathogenesis is thought to involve …

Novel therapeutic approaches for pulmonary fibrosis

A Datta, CJ Scotton… - British journal of …, 2011 - Wiley Online Library
Pulmonary fibrosis represents the end stage of a number of heterogeneous conditions and
is, to a greater or lesser degree, the hallmark of the interstitial lung diseases. It is …

Pathogenetic pathways and novel pharmacotherapeutic targets in idiopathic pulmonary fibrosis

KM Antoniou, A Pataka, D Bouros… - Pulmonary pharmacology …, 2007 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a poorly understood disease that usually leads to death
within 5 years of diagnosis. Despite our better understanding of IPF pathogenesis, the …

Oxidant/antioxidant disequilibrium in idiopathic pulmonary fibrosis pathogenesis

P Cameli, A Carleo, L Bergantini, C Landi, A Prasse… - Inflammation, 2020 - Springer
Idiopathic pulmonary fibrosis is characterised by abnormal reepithelialisation and
remodelling consequent to persistent stimuli or injury. The involvement of oxidative stress in …

[PDF][PDF] Idiopathic pulmonary fibrosis-a disorder of alveolar wound repair?

T Geiser - Swiss medical weekly, 2003 - smw.ch
Idiopathic pulmonary fibrosis (IPF) is a chronic and usually progressive lung disorder of
unknown aetiology. Conventional management of patients with IPF has been primarily …

The role of inflammation in the pathogenesis of idiopathic pulmonary fibrosis

BD Bringardner, CP Baran, TD Eubank… - Antioxidants & redox …, 2008 - liebertpub.com
The role of inflammation in idiopathic pulmonary fibrosis (IPF) is controversial. If
inflammation were critical to the disease process, lung pathology would demonstrate an …