Machine learning models to predict disease progression among veterans with hepatitis C virus

MA Konerman, LA Beste, T Van, B Liu, X Zhang, J Zhu… - PloS one, 2019 - journals.plos.org
Background Machine learning (ML) algorithms provide effective ways to build prediction
models using longitudinal information given their capacity to incorporate numerous predictor …

Improvement of predictive models of risk of disease progression in chronic hepatitis C by incorporating longitudinal data

MA Konerman, Y Zhang, J Zhu, PDR Higgins… - Hepatology, 2015 - journals.lww.com
Existing predictive models of risk of disease progression in chronic hepatitis C have limited
accuracy. The aim of this study was to improve upon existing models by applying novel …

Assessing risk of fibrosis progression and liver-related clinical outcomes among patients with both early stage and advanced chronic hepatitis C

MA Konerman, D Lu, Y Zhang, M Thomson, J Zhu… - PloS one, 2017 - journals.plos.org
Objective Assessing risk of adverse outcomes among patients with chronic liver disease has
been challenging due to non-linear disease progression. We previously developed accurate …

Data mining model using simple and readily available factors could identify patients at high risk for hepatocellular carcinoma in chronic hepatitis C

M Kurosaki, N Hiramatsu, M Sakamoto, Y Suzuki… - Journal of …, 2012 - Elsevier
BACKGROUND & AIMS: Assessment of the risk of hepatocellular carcinoma (HCC)
development is essential for formulating personalized surveillance or antiviral treatment plan …

Assessment of a deep learning model to predict hepatocellular carcinoma in patients with hepatitis C cirrhosis

GN Ioannou, W Tang, LA Beste, MA Tincopa… - JAMA network …, 2020 - jamanetwork.com
Importance Deep learning, a family of machine learning models that use artificial neural
networks, has achieved great success at predicting outcomes in nonmedical domains …

[HTML][HTML] Novel machine learning models outperform risk scores in predicting hepatocellular carcinoma in patients with chronic viral hepatitis

GLH Wong, VWK Hui, Q Tan, J Xu, HW Lee, TCF Yip… - JHEP Reports, 2022 - Elsevier
Background & Aims Accurate hepatocellular carcinoma (HCC) risk prediction facilitates
appropriate surveillance strategy and reduces cancer mortality. We aimed to derive and …

Computational models of liver fibrosis progression for hepatitis C virus chronic infection

J Lara, FX López-Labrador, F González-Candelas… - BMC …, 2014 - Springer
Background Chronic infection with hepatitis C virus (HCV) is a risk factor for liver diseases
such as fibrosis, cirrhosis and hepatocellular carcinoma. HCV genetic heterogeneity was …

Personalized surveillance for hepatocellular carcinoma in cirrhosis–using machine learning adapted to HCV status

E Audureau, F Carrat, R Layese, C Cagnot… - Journal of …, 2020 - Elsevier
Background & Aims Refining hepatocellular carcinoma (HCC) surveillance programs
requires improved individual risk prediction. Thus, we aimed to develop algorithms based on …

[HTML][HTML] Predictors of progression through the cascade of care to a cure for hepatitis C patients using decision trees and random forests

JY Nakayama, J Ho, E Cartwright, R Simpson… - Computers in biology …, 2021 - Elsevier
Background This study uses machine learning techniques to identify sociodemographic and
clinical predictors of progression through the hepatitis C (HCV) cascade of care for patients …

Accurate prediction of HCC risk after SVR in patients with hepatitis C cirrhosis based on longitudinal data

Y Zou, M Yue, L Jia, Y Wang, H Chen, A Zhang, X Xia… - BMC cancer, 2023 - Springer
Background Most existing predictive models of hepatocellular carcinoma (HCC) risk after
sustained virologic response (SVR) are built on data collected at baseline and therefore …