Although classical models predict that G-protein-coupled receptors (GPCRs) function as
monomers, several recent studies acknowledge that GPCRs exist as dimeric or oligomeric …

Recently, many G-protein-coupled receptors (GPCRs) have been demonstrated to form
constitutive dimers consisting of identical or distinct monomeric subunits. The discovery of …

It is now generally accepted that G protein-coupled receptors (GPCRs) can exist as dimers
or as part of larger oligomeric complexes. Increasing evidence suggests that a dimer is the …

G protein-coupled receptors (GPCRs) are cell surface receptors that mediate physiological
responses to a diverse array of stimuli. GPCRs have traditionally been thought to act as …

The classical idea that G‐protein‐coupled receptors (GPCRs) function as monomeric
entities has been unsettled by the emerging concept of GPCR dimerization. Recent findings …

Most evidence indicates that, as for family CG protein–coupled receptors (GPCRs), family A
GPCRs form homo-and heteromers. Homodimers seem to be a predominant species, with …

G-protein-coupled receptors (GPCRs) comprise the largest family of transmembrane
receptors in the human genome that respond to a plethora of signals, including …

Almost all existing models for G‐protein‐coupled receptors (GPCRs) are based on the
occurrence of monomers. Recent studies show that many GPCRs are dimers. Therefore for …

Although highly controversial just a few years ago, the idea that G‐protein‐coupled
receptors (GPCRs) may undergo homo‐oligomerization or hetero‐oligomerization has …

In contrast to other families of cell surface receptors for which dimerization is an integral part
of the activation process, G-protein-coupled receptors (GPCRs) were thought, until recently …