Dendritic mRNA transport coupled with local regulation of translation enables neurons to
selectively alter the protein composition of individual postsynaptic sites. We have analyzed …

Transport of mRNAs to diverse neuronal locations via RNA granules serves an important
function in regulating protein synthesis within restricted sub-cellular domains. We recently …

The targeting of mRNAs to neuronal dendrites is an important protein sorting mechanism.
Recent studies have revealed that mRNAs are transported by molecular motors. The kinesin …

Local protein synthesis in dendrites enables neurons to selectively change the protein
complement of individual postsynaptic sites. Though it is generally assumed that this …

Motor protein-based active transport is essential for mRNA localization and local translation
in animal cells, yet how mRNA granules interact with motor proteins remains poorly …

Intracellular transport is fundamental for neuronal morphogenesis, function and survival.
Many proteins are selectively transported to either axons or dendrites. In addition, some …

Localization of mRNAs to postsynaptic sites and their subsequent translation is thought to
contribute to synapse-specific plasticity. However, the direct visualization of dendritic RNA …

In cells, mRNAs are transported to and positioned at subcellular areas to locally regulate
protein production. Recent studies have identified the kinesin-3 family member motor protein …

Subcellular localization of messenger RNA (mRNA) is a widespread phenomenon that can
impact the regulation and function of the encoded protein. In nonneuronal cells, specific …

KIF1Bβ is a kinesin-like, microtubule-based molecular motor protein involved in anterograde
axonal vesicular transport in vertebrate and invertebrate neurons. Certain KIF1Bβ isoforms …