Subcellular localization of messenger RNA (mRNA) is a widespread phenomenon that can
impact the regulation and function of the encoded protein. In nonneuronal cells, specific …

RNA localization and local translation are important for numerous cellular functions. In
mammals, a class of mRNAs localize to cytoplasmic protrusions in an APC-dependent …

In cells, mRNAs are transported to and positioned at subcellular areas to locally regulate
protein production. Recent studies have identified the kinesin-3 family member motor protein …

Neurons critically depend on regulated RNA localization and tight control of spatiotemporal
gene expression to maintain their morphological and functional integrity. Mutations in the …

KIF1Bβ is a kinesin-like, microtubule-based molecular motor protein involved in anterograde
axonal vesicular transport in vertebrate and invertebrate neurons. Certain KIF1Bβ isoforms …

Neurons require a well-coordinated intercellular transport system to maintain their normal
cellular function and morphology. The kinesin family of proteins (KIFs) fills this role by …

ABSTRACT KIF2A is a kinesin motor protein with essential roles in neural progenitor
division and axonal pruning during brain development. However, how different KIF2A …

Dendritic mRNA transport coupled with local regulation of translation enables neurons to
selectively alter the protein composition of individual postsynaptic sites. We have analyzed …

The kinesin motor protein Kif1b has previously been implicated in the axonal transport of
mitochondria and synaptic vesicles,. More recently, KIF1B has been associated with …

Complex neural circuitry requires stable connections formed by lengthy axons. To maintain
these functional circuits, fast transport delivers RNAs to distal axons where they undergo …