Physicochemical characterization of liposomes after ultrasound exposure–mechanisms of drug release

TJ Evjen, S Hupfeld, S Barnert, S Fossheim… - … of pharmaceutical and …, 2013 - Elsevier
Ultrasound is investigated as a novel drug delivery tool within cancer therapy. Non-thermal
ultrasound treatment of solid tumours post iv-injection of drug-carrying liposomes may …

Ultrasound enhancement of liposome-mediated cell transfection is caused by cavitation effects

S Koch, P Pohl, U Cobet, NG Rainov - Ultrasound in medicine & biology, 2000 - Elsevier
Cationic liposomes (CL) are widely used vectors for gene transfer. Recently, ultrasound (US)
was reported to enhance liposome-mediated gene transfer to eucaryotic cells in culture. The …

Ultrasound and microbubble mediated therapeutic delivery: Underlying mechanisms and future outlook

SM Chowdhury, L Abou-Elkacem, T Lee, J Dahl… - Journal of Controlled …, 2020 - Elsevier
Beyond the emerging field of oncological ultrasound molecular imaging, the recent
significant advancements in ultrasound and contrast agent technology have paved the way …

Characterization of cell membrane response to ultrasound activated microbubbles

TA Tran, JY Le Guennec, P Bougnoux… - IEEE transactions on …, 2008 - ieeexplore.ieee.org
Contrast agents for ultrasound imaging, composed of tiny gas microbubbles, have become a
reality in clinical routine. They are extensively used in radiology for detection and …

Ultrasonic drug delivery using micelles and liposomes

AM Martins, SE Ahmed, RF Vitor, G Husseini - 2016 - dspace.aus.edu
The encapsulation of drugs in nanocarriers revolutionized research in drug delivery,
especially in cancer chemotherapeutics. Several nanosystems have been developed …

Increasing the endothelial layer permeability through ultrasound-activated microbubbles

K Kooiman, M Emmer… - IEEE transactions on …, 2009 - ieeexplore.ieee.org
Drug delivery to a diseased tissue will be more efficient if the vascular endothelial
permeability is increased. Recent studies have shown that the permeability of single cell …

Ultrasonically triggered drug delivery: breaking the barrier

GA Husseini, WG Pitt, AM Martins - Colloids and surfaces B: Biointerfaces, 2014 - Elsevier
The adverse side-effects of chemotherapy can be minimized by delivering the therapeutics
in time and space to only the desired target site. Ultrasound offers one fairly non-invasive …

Membrane damage thresholds for pulsed or continuous ultrasound in phagocytic cells loaded with contrast agent gas bodies

DL Miller, C Dou - Ultrasound in medicine & biology, 2004 - Elsevier
Cell membrane damage induced by pulsed or continuous ultrasound (US) activation of
attached contrast agent gas bodies was examined in an in vitro model system. Monolayers …

Controlled permeation of cell membrane by single bubble acoustic cavitation

Y Zhou, K Yang, J Cui, JY Ye, CX Deng - Journal of controlled release, 2012 - Elsevier
Sonoporation is the membrane disruption generated by ultrasound and has been exploited
as a non-viral strategy for drug and gene delivery. Acoustic cavitation of microbubbles has …

[HTML][HTML] Modulation of the molecular arrangement in artificial and biological membranes by phospholipid-shelled microbubbles

D Carugo, M Aron, E Sezgin, JB de la Serna… - Biomaterials, 2017 - Elsevier
The transfer of material from phospholipid-coated microbubbles to cell membranes has
been hypothesized to play a role in ultrasound-mediated drug delivery. In this study, we …