Free radical scavenging properties of melanin: interaction of eu-and pheo-melanin models with reducing and oxidising radicals

M Różanowska, T Sarna, EJ Land… - Free Radical Biology and …, 1999 - Elsevier
The human skin and eye melanin is commonly viewed as an efficient photoprotective agent.
To elucidate the molecular mechanism of the melanin-dependent photoprotection, we …

Interaction of radicals from water radiolysis with melanin

T Sarna, B Pilas, EJ Land, TG Truscott - Biochimica et Biophysica Acta (BBA …, 1986 - Elsevier
Melanins are considered to be natural photoprotectors in the melanocytes and keratinocytes
of the skin. These pigments have also been suggested to play an important role in protection …

Time-resolved detection of melanin free radicals quenching reactive oxygen species

BLL Seagle, KA Rezai, EM Gasyna… - Journal of the …, 2005 - ACS Publications
Melanin, a ubiquitous, heterogeneous biological polymer composed of many different
monomers, contains a population of stationary, intrinsic semiquinone-like radicals …

The role of melanin as protector against free radicals in skin and its role as free radical indicator in hair

T Herrling, K Jung, J Fuchs - Spectrochimica Acta Part A: Molecular and …, 2008 - Elsevier
Throughout the body, melanin is a homogenous biological polymer containing a population
of intrinsic, semiquinone-like radicals. Additional extrinsic free radicals are reversibly photo …

Photoprotection versus photodamage: updating an old but still unsolved controversy about melanin

F Solano - Polymer International, 2016 - Wiley Online Library
Melanin is the main pigment in animal skin. It is a heterogeneous polyphenolic molecule
with a generalized absorption in the UV− visible range synthesized in melanocytes, a kind of …

Free radicals in human skin before and after exposure to light

MA Pathak, K Stratton - Archives of biochemistry and biophysics, 1968 - Elsevier
Human skin exhibited a stable electron spin resonance (ESR) signal before irradiation, only
if the samples were pigmented. The single almost symmetrical absorption peak with g …

Melanin

PA Riley - The international journal of biochemistry & cell biology, 1997 - Elsevier
Melanin is an irregular light-absorbing polymer containing indoles and other intermediate
products derived from the oxidation of tyrosine. Melanin is widely dispersed in the animal …

Photoprotective properties of skin melanin

JP Ortonne - British Journal of Dermatology, 2002 - academic.oup.com
Melanins are a ubiquitous class of biological pigments, which play an important role in the
photoprotection of skin. Recent advances in the chemistry of melanins have demonstrated …

Aggregation of eumelanin mitigates photogeneration of reactive oxygen species

JB Nofsinger, Y Liu, JD Simon - Free Radical Biology and Medicine, 2002 - Elsevier
Melanins protect tissue by absorption and rapid nonradiative, nonreactive dissipation of
ultraviolet (UV) light. However, melanins also produce reactive oxygen species (ROS) upon …

Dual role of melanins and melanin precursors as photoprotective and phototoxic agents: inhibition of ultraviolet radiation‐induced lipid peroxidation

S Schmitz, PD Thomas, TM Allen… - Photochemistry and …, 1995 - Wiley Online Library
Ultraviolet radiation (UVR) is one of the risk factors for skin cancer and the main inducer of
melanin pigmentation, the major protective mechanism of mammalian skin against radiation …