Randomized, double-blind, phase 2a trial of falciparum malaria vaccines RTS, S/AS01B and RTS, S/AS02A in malaria-naive adults: safety, efficacy, and immunologic …
KE Kester, JF Cummings… - Journal of Infectious …, 2009 - academic.oup.com
Background To further increase the efficacy of malaria vaccine RTS, S/AS02A, we tested the
RTS, S antigen formulated using the AS01B Adjuvant System (GlaxoSmithKline Biologicals) …
RTS, S antigen formulated using the AS01B Adjuvant System (GlaxoSmithKline Biologicals) …
Malaria vaccines: the 60-year journey of hope and final success—lessons learned and future prospects
AA El-Moamly, MA El-Sweify - Tropical Medicine and Health, 2023 - Springer
Background The world has made great strides towards beating malaria, although about half
of the world population is still exposed to the risk of contracting malaria. Developing an …
of the world population is still exposed to the risk of contracting malaria. Developing an …
Fractional third and fourth dose of RTS, S/AS01 malaria candidate vaccine: a phase 2a controlled human malaria parasite infection and immunogenicity study
JA Regules, SB Cicatelli, JW Bennett… - The Journal of …, 2016 - academic.oup.com
Background. Three full doses of RTS, S/AS01 malaria vaccine provides partial protection
against controlled human malaria parasite infection (CHMI) and natural exposure …
against controlled human malaria parasite infection (CHMI) and natural exposure …
A review of malaria vaccine clinical projects based on the WHO rainbow table
L Schwartz, GV Brown, B Genton, VS Moorthy - Malaria journal, 2012 - Springer
Abstract Development and Phase 3 testing of the most advanced malaria vaccine, RTS,
S/AS01, indicates that malaria vaccine R&D is moving into a new phase. Field trials of …
S/AS01, indicates that malaria vaccine R&D is moving into a new phase. Field trials of …
Evaluation of RTS, S/AS02A and RTS, S/AS01B in adults in a high malaria transmission area
ME Polhemus, SA Remich, BR Ogutu, JN Waitumbi… - PloS one, 2009 - journals.plos.org
Background This study advances the clinical development of the RTS, S/AS01B candidate
malaria vaccine to malaria endemic populations. As a primary objective it compares the …
malaria vaccine to malaria endemic populations. As a primary objective it compares the …
The future of the RTS, S/AS01 malaria vaccine: an alternative development plan
R Gosling, L von Seidlein - PLoS medicine, 2016 - journals.plos.org
The Future of the RTS,S/AS01 Malaria Vaccine: An Alternative Development Plan | PLOS
Medicine Skip to main content Advertisement PLOS Medicine Browse Current Issue Journal …
Medicine Skip to main content Advertisement PLOS Medicine Browse Current Issue Journal …
Towards eradication of malaria: is the WHO's RTS, S/AS01 vaccination effective enough?
N Arora, LC Anbalagan, AK Pannu - Risk Management and …, 2021 - Taylor & Francis
Background Recent advances in mosquito eradication and antimalarial treatments have
reduced the malaria burden only modestly. An effective malaria vaccine remains a high …
reduced the malaria burden only modestly. An effective malaria vaccine remains a high …
The promise of a malaria vaccine—are we closer?
MB Laurens - Annual review of microbiology, 2018 - annualreviews.org
Malaria vaccine development has rapidly advanced in the past decade. The very first phase
3 clinical trial of the RTS, S vaccine was completed with over 15,000 African infants and …
3 clinical trial of the RTS, S vaccine was completed with over 15,000 African infants and …
A randomized trial assessing the safety and immunogenicity of AS01 and AS02 adjuvanted RTS, S malaria vaccine candidates in children in Gabon
B Lell, S Agnandji, I Von Glasenapp, S Haertle… - PLoS one, 2009 - journals.plos.org
Background The malaria vaccine candidate antigen RTS, S includes parts of the pre-
erythrocytic stage circumsporozoite protein fused to the Hepatitis B surface antigen. Two …
erythrocytic stage circumsporozoite protein fused to the Hepatitis B surface antigen. Two …