Chemosensory dysfunction in COVID-19: integration of genetic and epidemiological data points to D614G spike protein variant as a contributing factor

R Butowt, K Bilinska… - ACS chemical …, 2020 - ACS Publications
After several months of rapid pandemic expansion, it is now apparent that the SARS-CoV-2
coronavirus interferes with smell and taste sensation in a substantial proportion of COVID-19 …

Prevalence of chemosensory dysfunction in COVID-19 patients: a systematic review and meta-analysis reveals significant ethnic differences

CS von Bartheld, MM Hagen… - ACS chemical …, 2020 - ACS Publications
A significant proportion of people who test positive for COVID-19 have chemosensory
deficits. However, the reported prevalence of these deficits in smell and taste varies widely …

Decreasing incidence of chemosensory changes by COVID‐19 variant

DH Coelho, ER Reiter, E French… - … –Head and Neck …, 2023 - Wiley Online Library
Anecdotal clinical observation suggests that rates of chemosensory dysfunction associated
with COVID‐19 infection may be decreasing. To investigate, the National COVID Cohort …

COVID-19 and the chemical senses: supporting players take center stage

KW Cooper, DH Brann, MC Farruggia, S Bhutani… - Neuron, 2020 - cell.com
The main neurological manifestation of COVID-19 is loss of smell or taste. The high
incidence of smell loss without significant rhinorrhea or nasal congestion suggests that …

Chemosensory dysfunction in patients with COVID-19: what do we learn from the global outbreak?

M Zeng, DY Wang, J Mullol, Z Liu - Current Allergy and Asthma Reports, 2021 - Springer
Abstract Purpose of Review Chemosensory dysfunction in the patients with COVID-19 has
been reported frequently in the studies from different regions of the world. However, the …

Direct neuronal infection of SARS-CoV-2 reveals cellular and molecular pathology of chemosensory impairment of COVID-19 patients

KS Lyoo, HM Kim, B Lee, YH Che, SJ Kim… - Emerging microbes & …, 2022 - Taylor & Francis
Patients with recent pandemic coronavirus disease 19 (COVID-19) complain of neurological
abnormalities in sensory functions such as smell and taste in the early stages of infection …

Coronaviruses and the chemical senses: past, present, and future

R Pellegrino, KW Cooper, A Di Pizio… - Chemical …, 2020 - academic.oup.com
A wealth of rapidly evolving reports suggests that olfaction and taste disturbances may be
manifestations of the novel COVID-19 pandemic. While otolaryngological societies …

More than smell—COVID-19 is associated with severe impairment of smell, taste, and chemesthesis

V Parma, K Ohla, MG Veldhuizen, MY Niv… - Chemical …, 2020 - academic.oup.com
Recent anecdotal and scientific reports have provided evidence of a link between COVID-19
and chemosensory impairments, such as anosmia. However, these reports have …

Assessing the extent and timing of chemosensory impairments during COVID-19 pandemic

C Cecchetto, A Di Pizio, F Genovese, O Calcinoni… - Scientific reports, 2021 - nature.com
Chemosensory impairments have been established as a specific indicator of COVID-19.
They affect most patients and may persist long past the resolution of respiratory symptoms …

The D614G virus mutation enhances anosmia in COVID-19 patients: evidence from a systematic review and meta-analysis of studies from South Asia

CS von Bartheld, MM Hagen… - ACS Chemical …, 2021 - ACS Publications
The prevalence of chemosensory dysfunction in patients with COVID-19 varies greatly
between populations. It is unclear whether such differences are due to factors at the level of …