SARS-CoV-2 signaling pathway map: A functional landscape of molecular mechanisms in COVID-19

DAB Rex, S Dagamajalu, RK Kandasamy… - Journal of Cell …, 2021 - Springer
Abstract Coronavirus disease (COVID-19) is caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2). COVID-19 has been declared a pandemic by WHO. The …

[HTML][HTML] COVID-19 signalome: Pathways for SARS-CoV-2 infection and impact on COVID-19 associated comorbidity

K Lundstrom, A Hromić-Jahjefendić, E Bilajac… - Cellular …, 2023 - Elsevier
The COVID-19 pandemic has been the focus of research the past two years. The major
breakthrough was made by discovering pathways related to SARS-CoV-2 infection through …

The roles of signaling pathways in SARS-CoV-2 infection; lessons learned from SARS-CoV and MERS-CoV

N Hemmat, Z Asadzadeh, NK Ahangar… - Archives of …, 2021 - Springer
The number of descriptions of emerging viruses has grown at an unprecedented rate since
the beginning of the 21 st century. Severe acute respiratory syndrome coronavirus 2 (SARS …

Inflammatory pathways in COVID‐19: Mechanism and therapeutic interventions

Y Jiang, T Zhao, X Zhou, Y Xiang… - MedComm, 2022 - Wiley Online Library
Abstract The 2019 coronavirus disease (COVID‐19) pandemic has become a global crisis.
In the immunopathogenesis of COVID‐19, SARS‐CoV‐2 infection induces an excessive …

[HTML][HTML] COVID-19 signalome: Potential therapeutic interventions

K Lundstrom, A Hromić-Jahjefendić, E Bilajac… - Cellular signalling, 2023 - Elsevier
The COVID-19 pandemic has triggered intensive research and development of drugs and
vaccines against SARS-CoV-2 during the last two years. The major success was especially …

Dysregulation of cell signaling by SARS-CoV-2

RK Suryawanshi, R Koganti, A Agelidis, CD Patil… - Trends in …, 2021 - cell.com
Pathogens usurp host pathways to generate a permissive environment for their propagation.
The current spread of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) …

[HTML][HTML] Cellular and molecular pathways of COVID-19 and potential points of therapeutic intervention

JP Hussman - Frontiers in pharmacology, 2020 - frontiersin.org
With the objective of linking early findings relating to the novel SARS-CoV-2 coronavirus
with potentially informative findings from prior research literature and to promote …

[HTML][HTML] Molecular pathways involved in COVID-19 and potential pathway-based therapeutic targets

M Farahani, Z Niknam, LM Amirabad… - Biomedicine & …, 2022 - Elsevier
Deciphering the molecular downstream consequences of severe acute respiratory
syndrome coronavirus (SARS-CoV)− 2 infection is important for a greater understanding of …

Inflammatory pathways and potential therapies for COVID-19: A mini review

AM Dabbish, N Yonis, M Salama… - European Journal …, 2021 - journals.sagepub.com
The public health crisis of the novel coronavirus disease (COVID-19) is alarming since
January 2020. COVID-19 genome (SARS-CoV-2) is related to other highly pathogenic …

Immune response in COVID-19: addressing a pharmacological challenge by targeting pathways triggered by SARS-CoV-2

M Catanzaro, F Fagiani, M Racchi, E Corsini… - Signal transduction and …, 2020 - nature.com
To date, no vaccines or effective drugs have been approved to prevent or treat COVID-19
and the current standard care relies on supportive treatments. Therefore, based on the fast …