Reduced humoral response 3 months following BNT162b2 vaccination in SARS-CoV-2 uninfected residents of long-term care facilities

M Trigueros, E Pradenas, D Palacín… - Age and …, 2022 - academic.oup.com
Background SARS-CoV-2 vaccination is the most effective strategy to protect older residents
of long-term care facilities (LTCF) against severe COVID-19, but primary vaccine responses …

Characterization of the humoral immune response to BNT162b2 in elderly residents of long-term care facilities five to seven months after vaccination

M Delbrück, S Hoehl, T Toptan, B Schenk, K Grikscheit… - medrxiv, 2021 - medrxiv.org
The elderly residing in long-term care facilities (LTCFs) are a group at high risk for COVID-
19. Hence, monitoring of the vaccine-based immunity has a pivotal role in identifying …

Immunogenicity of the BNT162b2 mRNA COVID-19 vaccine in older residents of a long-term care facility: relation with age, frailty and prior infection status

P Seiffert, A Konka, J Kasperczyk, J Kawa, M Lejawa… - Biogerontology, 2022 - Springer
Clinical and biological assessment of the COVID-19 vaccine efficacy in the frail population is
of crucial importance. The study focuses on measuring the levels of anti-SARS-CoV-2 IgG …

Antibody response 3 months after 2 doses of BNT162b2 mRNA COVID-19 vaccine in residents of long-term care facilities

R Causa, D Almagro-Nievas, M Rivera-Izquierdo… - Gerontology, 2022 - karger.com
Background: Older adults living in long-term care facilities (LTCFs) are at increased risk for
severe outcomes from COVID-19 and were identified as a priority group in COVID-19 …

[HTML][HTML] Weak humoral immune reactivity among residents of long-term care facilities following one dose of the BNT162b2 mRNA COVID-19 vaccine

MA Brockman, F Mwimanzi, Y Sang, K Ng, O Agafitei… - medRxiv, 2021 - ncbi.nlm.nih.gov
Background. Several Canadian provinces are extending the interval between COVID-19
vaccine doses to increase population vaccine coverage more rapidly. However …

BNT162b2 vaccination elicits strong serological immune responses against SARS-CoV-2 including variants of concern in elderly convalescents

B Jahrsdörfer, D Fabricius, J Scholz, C Ludwig… - Frontiers in …, 2021 - frontiersin.org
Elderly residents of long-term care facilities (LTCFs) have long been underrepresented in
studies on vaccine efficacy, particularly in light of currently emerging variants of concern …

Humoral and cellular responses to COVID-19 vaccination indicate the need for post-vaccination testing in frail population

W Witkowski, S Gerlo, E De Smet, M Wejda, D Acar… - Vaccines, 2022 - mdpi.com
Despite the high efficacy of the BNT162b2 vaccine in the general population, data on its
immunogenicity among frail elderly individuals are limited. Recently, levels of anti-SARS …

Impaired functional T-cell response to SARS-CoV-2 after two doses of BNT162b2 mRNA vaccine in older people

J Demaret, B Corroyer-Simovic, EK Alidjinou… - Frontiers in …, 2021 - frontiersin.org
Long-term care facility (LTCF) older residents display physiological alterations of cellular
and humoral immunity that affect vaccine responses. Preliminary reports suggested a low …

Neutralising antibody responses to SARS-CoV-2 omicron among elderly nursing home residents following a booster dose of BNT162b2 vaccine: A community-based …

T Bruel, L Pinaud, L Tondeur, D Planas… - …, 2022 - thelancet.com
Background The protective immunity against omicron following a BNT162b2 Pfizer booster
dose among elderly individuals (ie, those aged> 65 years) is not well characterised …

Immune responses against SARS-CoV-2 WT and delta variant in elderly BNT162b2 vaccinees

M Jäger, ST Sonnleitner, S Dichtl, E Lafon… - Frontiers in …, 2022 - frontiersin.org
Background Residents of nursing homes are one of the most vulnerable groups during the
severe acute syndrome coronavirus 2 (SARS-CoV-2) pandemic. The aim of this study was to …