This article provides an overview of the development, structure and activity of various metal
complexes with anti-cancer activity. Chemical researchers continue to work on the …

This article provides an overview of the development, structure and activity of various metal
complexes with anti-cancer activity. Chemical researchers continue to work on the …

Research into cancer therapeutics has uncovered various potential medications based on
metal-containing scaffolds after the discovery and clinical applications of cisplatin as an anti …

For the past 41 years, metal-based drugs have been widely used for the treatment of cancer.
Cisplatin and follow-up drugs carboplatin (Paraplatin™) and oxaliplatin (Eloxatin™) have …

Cancer diagnostics and therapy that include metal-based pharmaceuticals have improved
over the past decades. The therapeutic importance and application of metals and their …

The constant search for successful cancer therapies lasts for decades. Apart from the huge
scientific effort and enormous sum of spent money, only a small amount of newly developed …

Metal-based complexes have tremendous capacity to interact with biological molecules and
modify their actions. Due to their ability to modify enzymatic action, metabolism and …

Anticancer platinum-based drugs are widely used in the treatment of a variety of tumorigenic
diseases. They have been identified to target DNA and thereby induce apoptosis in cancer …

Metallodrugs offer potential for unique mechanism of drug action based on the choice of the
metal, its oxidation state, the types and number of coordinated ligands and the coordination …

In the past, metal-based compounds were widely used in the treatment of disease
conditions, but the lack of clear distinction between the therapeutic and toxic doses was a …