Low serum apelin levels are associated with mild cognitive impairment in Type 2 diabetic patients

Y Jiang, S Wang, X Liu - BMC Endocrine Disorders, 2022 - Springer
Background Apelin is a new adipokine that is secreted by adipocytes, and is associated with
insulin resistance (IR), inflammation, and obesity. This study was designed to investigate the …

[HTML][HTML] Study of serum apelin and Insulin Resistance in type 2 diabetes Mellitus patients with or without obesity

C Mund, CK Kellellu, R Rattan, S Mahapatra… - Cureus, 2023 - ncbi.nlm.nih.gov
Introduction: Type 2 diabetes mellitus (T2DM) is a chronic disorder characterized by
persistent hyperglycemia. Chronic hyperglycemia in diabetes mellitus can cause …

Altered glucose homeostasis is associated with increased serum apelin levels in type 2 diabetes mellitus

MG Cavallo, F Sentinelli, I Barchetta, C Costantino… - PloS one, 2012 - journals.plos.org
Background Apelin is an adipokine that plays a role in the regulation of glucose
homeostasis and in obesity. The relationship between apelin serum concentration and …

Low plasma apelin levels in newly diagnosed type 2 diabetes mellitus

G Erdem, T Dogru, I Tasci, A Sonmez… - Experimental and …, 2008 - thieme-connect.com
Objective: To investigate blood apelin concentrations in patients with newly diagnosed and
untreated type 2 diabetes mellitus (T2DM) who had no additional disorder and to investigate …

Apelin levels are increased in morbidly obese subjects with type 2 diabetes mellitus

F Soriguer, L Garrido-Sanchez, S Garcia-Serrano… - Obesity surgery, 2009 - Springer
Background The physiological role of apelin in obesity and diabetes remains unclear.
Although apelin has been studied in persons with different conditions, no studies have yet …

An overview on biological functions and emerging therapeutic roles of apelin in diabetes mellitus

FG Alipour, MR Ashoori… - Diabetes & Metabolic …, 2017 - Elsevier
Type 2 diabetes mellitus is a common type of diabetes and considered as multifactorial
disease. Apelin is an adipokine which secreted from white adipose tissue and involved in …

[HTML][HTML] Effects of weight loss and exercise on apelin serum concentrations and adipose tissue expression in human obesity

J Krist, K Wieder, N Klöting, A Oberbach, S Kralisch… - Obesity facts, 2013 - karger.com
Objective: Apelin is an adipokine which plays a role in the regulation of glucose
homeostasis and may contribute to the link between increased adipose tissue mass and …

Plasma apelin: a novel biomarker for predicting diabetes

WY Ma, TY Yu, JN Wei, CS Hung, MS Lin, YJ Liao… - Clinica chimica acta, 2014 - Elsevier
Background Apelin regulates insulin sensitivity and secretion in animals. However, whether
plasma apelin predicts incident diabetes in humans remains unknown. Methods We studied …

Elevated plasma levels of apelin in children with type 1 diabetes mellitus

C Meral, E Tascilar, F Karademir, IA Tanju, F Cekmez… - 2010 - degruyter.com
Background: Apelin is a novel adipocytokine produced by white adipose tissue that binds
the APJ receptor with high affinity. Insulin may have a role in regulation of apelin synthesis …

Circulating a pelin is increased in patients with type 1 or type 2 diabetes and is associated with better glycaemic control

M Habchi, L Duvillard, V Cottet, MC Brindisi… - Clinical …, 2014 - Wiley Online Library
Context Apelin is an adipokine expressed in several tissues and it appears to be involved in
energy metabolism. Objective The aim of this study was to determine serum apelin levels in …