Virtually all eukaryotes actively transport or position intracellular components (for example,
chromosomes or membrane-bounded organelles), and some cells have developed means …

Cellular polarization dependsuponthe asymmetrictransport of componentswithin the cell,
often along microtubule paths. Kinesin and cytoplasmic dynein are the most abundant …

It has been thought that motile structures within the cell are driven toward the plus and minus
ends of microtubules by the ATPases, kinesin and dynein, respectively. Recently obtained …

The cellular processes of transport, division and, possibly, early development all involve
microtubule‐based motors. Recent work shows that, unexpectedly, many of these cellular …

Microtubule-based motility is precisely regulated, and the targets of regulation may be the
motor proteins, the microtubules, or both components of this intricately controlled system …

Among the most interesting proteins associated with microtubules are the energy-
transducing ATPases, known as microtubule motors. These motor proteins, which. are able …

Microtubules are found in almost all eukaryotic cells and serve a number of important
functions in cell motility. They are the principal structural comн ponents of the mitotic spindle …

Many of the motions by and within cells are dependent on mechanochemical enzymes that
interact with cytoplasmic filaments to generate force. For example, myosin interacts with …

A family of proteins related to the microtubule motor, kinesin, is emerging. Members of this
family, which includes both plus-and minus-end motors, are involved in nuclear functions …

Organelle transport along microtubules can be reconstituted using isolated components,
allowing this complex motility process to be dissected biochemically. This approach has led …