Immunopathogenesis and immunogenetic variants in COVID-19

P Sagulkoo, K Plaimas, A Suratanee… - Current …, 2022 - ingentaconnect.com
Coronavirus disease 2019 (COVID-19) continues to spread globally despite the discovery of
vaccines. Many people die due to COVID-19 as a result of catastrophic consequences, such …

Immunogenetic association underlying severe COVID-19

K McCoy, A Peterson, Y Tian, Y Sang - Vaccines, 2020 - mdpi.com
SARS-CoV2 has caused the current pandemic of new coronavirus disease 2019 (COVID-
19) worldwide. Clinical outcomes of COVID-19 illness range broadly from asymptotic and …

Unraveling the immune response in severe COVID-19

L Rodriguez, P Brodin - Journal of Clinical Immunology, 2020 - Springer
An outbreak of coronavirus disease 2019 (COVID-19) emerged in China's Hubei province
and spread rapidly across the globe leading to millions of cases worldwide. The causative …

The role of immunogenetics in COVID-19

F Pojero, G Candore, C Caruso, D Di Bona… - International Journal of …, 2021 - mdpi.com
Coronavirus disease 2019 (COVID-19) is induced by SARS-CoV-2 and may arise as a
variety of clinical manifestations, ranging from an asymptomatic condition to a life …

The COVID-19 inflammation and high mortality mechanism trigger

S Stróż, P Kosiorek, A Stasiak-Barmuta - Immunogenetics, 2024 - Springer
The COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) lasted from March 2020 to May 2023, infecting over 689 million and causing …

Single nucleotide polymorphisms located in TNFA, IL1RN, IL6R, and IL6 genes are associated with COVID‐19 risk and severity in an Iranian population

M Rokni, M Sarhadi, M Heidari Nia… - Cell Biology …, 2022 - Wiley Online Library
Cytokines play pivotal functions in coronavirus disease 2019 (COVID‐19) pathogenesis.
However, little is known about the rationale and importance of genetic variations associated …

[HTML][HTML] SARS-CoV-2 meta-interactome suggests disease-specific, autoimmune pathophysiologies and therapeutic targets

G Bellucci, C Ballerini, R Mechelli, R Bigi… - …, 2020 - ncbi.nlm.nih.gov
Background: Severe coronavirus disease 2019 (COVID-19) is associated with multiple
comorbidities and is characterized by an auto-aggressive inflammatory state leading to …

[HTML][HTML] IL10RB as a key regulator of COVID-19 host susceptibility and severity

G Voloudakis, G Hoffman, S Venkatesh, KM Lee… - medRxiv, 2021 - ncbi.nlm.nih.gov
Background Recent efforts have identified genetic loci that are associated with coronavirus
disease 2019 (COVID-19) infection rates and disease outcome severity. Translating these …

[HTML][HTML] Genetics insight for COVID-19 susceptibility and severity: a review

I Fricke-Galindo, R Falfán-Valencia - Frontiers in immunology, 2021 - frontiersin.org
Coronavirus disease (COVID-19) presents a broad spectrum of clinical manifestations
ranging from an asymptomatic to a severe clinical course. The host genetic background …

[HTML][HTML] Germline genetic variants of viral entry and innate immunity may influence susceptibility to SARS-CoV-2 infection: toward a polygenic risk score for risk …

VK Grolmusz, A Bozsik, J Papp, A Patócs - Frontiers in Immunology, 2021 - frontiersin.org
The ongoing COVID-19 pandemic caused by the novel coronavirus, SARS-CoV-2 has
affected all aspects of human society with a special focus on healthcare. Although older …