An immunological review of SARS-CoV-2 infection and vaccine serology: innate and adaptive responses to mRNA, adenovirus, inactivated and protein subunit …

SA Al-Sheboul, B Brown, Y Shboul, I Fricke… - Vaccines, 2022 - mdpi.com
The coronavirus disease 2019 (COVID-19) pandemic is caused by the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) virus, which is defined by its positive …

Nasal vaccination against SARS-CoV-2: Synergistic or alternative to intramuscular vaccines?

M Tiboni, L Casettari, L Illum - International journal of pharmaceutics, 2021 - Elsevier
It is striking that all marketed SARS-CoV-2 vaccines are developed for intramuscular
administration designed to produce humoral and cell mediated immune responses …

[HTML][HTML] SARS-CoV-2 vaccines in advanced clinical trials: Where do we stand?

S Chakraborty, V Mallajosyula, CM Tato, GS Tan… - Advanced drug delivery …, 2021 - Elsevier
The ongoing SARS-CoV-2 pandemic has led to the focused application of resources and
scientific expertise toward the goal of developing investigational vaccines to prevent COVID …

COVID‐19 vaccinations: the unknowns, challenges, and hopes

K Mohamed, P Rzymski, MS Islam… - Journal of medical …, 2022 - Wiley Online Library
The entire world has been suffering from the coronavirus disease 2019 (COVID‐19)
pandemic since March 11, 2020. More than a year later, the COVID‐19 vaccination brought …

Protective mucosal immunity against SARS-CoV-2 after heterologous systemic prime-mucosal boost immunization

D Lapuente, J Fuchs, J Willar, A Vieira Antão… - Nature …, 2021 - nature.com
Several effective SARS-CoV-2 vaccines are currently in use, but effective boosters are
needed to maintain or increase immunity due to waning responses and the emergence of …

COVID-19 vaccines currently under preclinical and clinical studies, and associated antiviral immune response

S Jain, H Batra, P Yadav, S Chand - Vaccines, 2020 - mdpi.com
With a death toll of over one million worldwide, the COVID-19 pandemic caused by SARS-
CoV-2 has become the most devastating humanitarian catastrophe in recent decades. The …

Fighting the SARS-CoV-2 pandemic requires a global approach to understanding the heterogeneity of vaccine responses

JA Tomalka, MS Suthar, SG Deeks, RP Sekaly - Nature Immunology, 2022 - nature.com
Host genetic and environmental factors including age, biological sex, diet, geographical
location, microbiome composition and metabolites converge to influence innate and …

ChAdOx1‐S adenoviral vector vaccine applied intranasally elicits superior mucosal immunity compared to the intramuscular route of vaccination

M Cokarić Brdovčak, J Materljan… - European journal of …, 2022 - Wiley Online Library
COVID‐19 vaccines prevent severe forms of the disease, but do not warrant complete
protection against breakthrough infections. This could be due to suboptimal mucosal …

Distinct features and functions of systemic and mucosal humoral immunity among SARS-CoV-2 convalescent individuals

SE Butler, AR Crowley, H Natarajan, S Xu… - Frontiers in …, 2021 - frontiersin.org
Understanding humoral immune responses to SARS-CoV-2 infection will play a critical role
in the development of vaccines and antibody-based interventions. We report systemic and …

Safety and immunogenicity of intramuscular, single-dose V590 (rVSV-SARS-CoV-2 Vaccine) in healthy adults: Results from a phase 1 randomised, double-blind …

JA Robbins, D Tait, Q Huang, S Dubey, T Crumley… - …, 2022 - thelancet.com
Background Vaccines against COVID-19 are needed to overcome challenges associated
with mitigating the global pandemic. We report the safety and immunogenicity of V590, a live …