Markov Chains to Explore the Nanosystems for the Biophysical Studies of Cancers

KA Al-Utaibi, A Nutini, SM Sait, S Iqbal - Biophysical Reviews and …, 2024 - World Scientific
The immune response is essential for the human body to function well and to survive against
the sudden and chronic diseases such as viral & bacterial infections and cancers. In the …

Investigating tumour micro environment dynamics based on cytokine-mediated innate-adaptive immunity

IM Amima - 2018 - scholar.sun.ac.za
Cancer is a leading cause of death worldwide, yet much is still unknown about its
mechanism of establishment, recurrence cycle and destruction. It is known that the …

Computational advances in chronic diseases diagnostics and therapy-I

G Selvaraj, C Selvaraj, DQ Wei - Current Drug Targets, 2020 - ingentaconnect.com
Recently, omics data explosion is transforming diagnostics research and healthcare
industry, offering both opportunities and challenges. Huge data of chronic disease diagnosis …

From Reductionistic Approach to Systems Immunology Approach for the Understanding of Tumor Microenvironment

N Koelsch, MH Manjili - International Journal of Molecular Sciences, 2023 - mdpi.com
The tumor microenvironment (TME) is a complex and dynamic ecosystem that includes a
variety of immune cells mutually interacting with tumor cells, structural/stromal cells, and …

[PDF][PDF] The Interface of Cancer, Their Microenvironment and Nanotechnology.

N Roque, D Matias, J Balça-Silva… - … (Tech Science Press), 2022 - researchgate.net
Cancer is one of the deadliest diseases with a cure far from being found. Despite the
extraordinary advances in the therapy approaches, only a few patients respond to …

[PDF][PDF] Multi-scale modeling approaches in systems biology towards the assessment of cancer treatment dynamics: adoption of middle-out rationalist approach

D Majumder, A Mukherjee - Advances in Cancer Research & …, 2013 - ibimapublishing.com
Complex diseases like cancer are being viewed through the recent approach of systems
biology (SB) with a hope that it could provide a better assessment about the disease …

[PDF][PDF] Comparative analysis of biological networks using Markov chains and hidden Markov models

BJ Yoon, X Qian, S Sahraeian - IEEE Signal Processing Magzines, 2011 - academia.edu
The diverse cellular mechanisms that sustain the life of living organisms are carried out by
numerous biomolecules, such as DNAs, RNAs, and proteins. During the past decades …

Providing a Stochastic Petri Net Model for Interactions of the Immune System and B16-F10 Tumor Cells in order to Investigate the Effect of Myeloid-Derived …

S Shafiekhani, S Rahbar, F Akbarian… - Frontiers in Biomedical …, 2017 - fbt.tums.ac.ir
Purpose: Using mathematical models for cancer treatment had excellent outcomes in recent
years. Modeling of the tumor-immune interactions is possible by several mathematical …

Algorithmic and stochastic representations of gene regulatory networks and protein-protein interactions

A Alexiou, S Chatzichronis, A Perveen… - Current Topics in …, 2019 - ingentaconnect.com
Background: Latest studies reveal the importance of Protein-Protein interactions on
physiologic functions and biological structures. Several stochastic and algorithmic methods …

On a nonlinear system modeling darwinian dynamics and the immune response to cancer evolution

A Bellouquid, M CH-CHAOUI… - … on Mathematical and …, 2016 - World Scientific
In this paper a mathematical model, at the cellular level, related to the onset and evolution of
cancer cells contrasted by the immune system, is derived by tools of kinetic theory of active …