Cytokine prediction of mortality in COVID19 patients

M Mandel, G Harari, M Gurevich, A Achiron - Cytokine, 2020 - Elsevier
Abstract Coronavirus disease 2019 (COVID19) is a life-threatening infection with uncertain
progression and outcome. Assessing the severity of the disease for worsening patients is of …

Prospective validation study of prognostic biomarkers to predict adverse outcomes in patients with COVID-19: a study protocol

B Tang, M Shojaei, Y Wang, M Nalos, A Mclean… - BMJ open, 2021 - bmjopen.bmj.com
Introduction Accurate triage is an important first step to effectively manage the clinical
treatment of severe cases in a pandemic outbreak. In the current COVID-19 global …

Rapid diagnosis of SARS-CoV-2 infection by detecting IgG and IgM antibodies with an immunochromatographic device: a prospective single-center study

F Pérez-García, R Pérez-Tanoira, J Romanyk, T Arroyo… - MedRxiv, 2020 - medrxiv.org
Objectives SARS-CoV-2 infection constitutes a diagnostic challenge in patients from 2-3
weeks after the onset of symptoms, due to the low positivity rate of the PCR, especially in …

An artificial neural network classification method employing longitudinally monitored immune biomarkers to predict the clinical outcome of critically ill COVID-19 …

G Martinez, A Garduno, A Mahmud-Al-Rafat… - PeerJ, 2022 - peerj.com
Background The severe form of COVID-19 can cause a dysregulated host immune
syndrome that might lead patients to death. To understand the underlying immune …

Utility of routine laboratory biomarkers to detect COVID-19: a systematic review and meta-analysis

J Suklan, J Cheaveau, S Hill, SG Urwin, K Green… - Viruses, 2021 - mdpi.com
No routine laboratory biomarkers perform well enough in diagnosing COVID-19 in isolation
for them to be used as a standalone diagnostic test or to help clinicians prioritize patients for …

Biomarkers of cytokine storm as red flags for severe and fatal COVID-19 cases: A living systematic review and meta-analysis

AKG Melo, KM Milby, ALMA Caparroz, ACPN Pinto… - PloS one, 2021 - journals.plos.org
Objective To describe the laboratory parameters and biomarkers of the cytokine storm
syndrome associated with severe and fatal COVID-19 cases. Methods A search with …

[PDF][PDF] Elevated plasma levels of selective cytokines in COVID-19 patients reflect viral load and lung injury

Y Liu, C Zhang, F Huang, Y Yang, F Wang… - National Science …, 2020 - academic.oup.com
A recent outbreak of pneumonia in Wuhan, China was found to be caused by a 2019 novel
coronavirus (2019-nCoV or SARS-CoV-2 or HCoV-19). We previously reported the clinical …

Clinical severity classes in COVID-19 pneumonia have distinct immunological profiles, facilitating risk stratification by machine learning

L Wiffen, LG D'Cruz, T Brown, TW Higenbottam… - Frontiers in …, 2023 - frontiersin.org
Objective Clinical triage in coronavirus disease 2019 (COVID-19) places a heavy burden on
senior clinicians during a pandemic situation. However, risk stratification based on serum …

Could IL-6 predict the clinical severity of COVID-19?

G Aykal, H Esen, D Seyman… - Turkish Journal of …, 2021 - degruyter.com
Objectives An excessive inflammatory response to SARS-CoV-2 is thought to be a major
cause of disease severity in COVID-19. The aim herein was to determine the prognostic …

COVID19 biomarkers: What did we learn from systematic reviews?

S Semiz - Frontiers in cellular and infection microbiology, 2022 - frontiersin.org
The coronavirus disease 2019 (COVID19) pandemic continues to represent a substantial
public health concern. It can rapidly progress to severe disease, with poor prognosis and a …