Over the past 15 years, the advent of massively parallel sequencing (MPS) techniques
(previously called next generation sequencing [NGS] techniques), has tremendously …

It has long been known that inherited kidney disor-ders such as polycystic kidney disease
(PKD) can be caused by mutations in a single gene. These disorders are termed monogenic …

Abstract Purpose of Review The role of genetics in renal disorders is being increasingly
recognized, prompting the need to describe and address barriers to meaningful …

Hundreds of different genetic causes of chronic kidney disease are now recognized, and
while individually rare, taken together they are significant contributors to both adult and …

Rationale & Objective There has been an increasing demand for the expertise provided by a
renal genetics clinic. Such programs are limited in the United States and typically operate in …

The Kidney-Genetics Documentation Kidney-Genetics Documentation Preface Objective
Methods Results Conclusion Outlook 1 Analyses result tables 1.1 Main table: Merged …

Our understanding of the genetic contri-bution to human disease continues to increase at a
phenomenal pace. The contribution of genetic research to understanding kidney disease …

Abstract Background and Aims Genetic insights are becoming increasingly influential in the
understanding and treatment of various kidney diseases (KD). Hundreds of genes …

Worldwide, more than 850 million people have chronic kidney disease (CKD)(Jager et al.,
2019). CKD can be caused by a variety of individual diseases including primary kidney …

The kidney is subject to a wide range of abnormalities, many of which have a significant
hereditable component. Next generation sequencing is increasingly bringing the genetic …