Interaction of severe acute respiratory syndrome-associated coronavirus with dendritic cells

M Spiegel, K Schneider, F Weber… - Journal of general …, 2006 - microbiologyresearch.org
Severe acute respiratory syndrome (SARS) of humans is caused by a novel coronavirus of
zoonotic origin termed SARS-associated coronavirus (SARS-CoV). The virus induces …

Chemokine up-regulation in SARS-coronavirus–infected, monocyte-derived human dendritic cells

HKW Law, CY Cheung, HY Ng, SF Sia, YO Chan… - Blood, 2005 - ashpublications.org
Lymphopenia and increasing viral load in the first 10 days of severe acute respiratory
syndrome (SARS) suggested immune evasion by SARS-coronavirus (CoV). In this study, we …

Severe acute respiratory syndrome and the innate immune responses: modulation of effector cell function without productive infection

CTK Tseng, LA Perrone, H Zhu, S Makino… - The Journal of …, 2005 - journals.aai.org
Severe acute respiratory syndrome (SARS) caused by a novel human coronavirus (CoV),
designated SARS-CoV, is a highly contagious respiratory disease with the lungs as a major …

Severe acute respiratory syndrome (SARS) coronavirus-induced lung epithelial cytokines exacerbate SARS pathogenesis by modulating intrinsic functions of …

T Yoshikawa, T Hill, K Li, CJ Peters… - Journal of virology, 2009 - Am Soc Microbiol
Severe acute respiratory syndrome (SARS), which is caused by a novel coronavirus (CoV),
is a highly communicable disease with the lungs as the major pathological target. Although …

Cytokine responses in severe acute respiratory syndrome coronavirus-infected macrophages in vitro: possible relevance to pathogenesis

CY Cheung, LLM Poon, IHY Ng, W Luk, SF Sia… - Journal of …, 2005 - Am Soc Microbiol
The pathogenesis of severe acute respiratory syndrome (SARS) remains unclear.
Macrophages are key sentinel cells in the respiratory system, and it is therefore relevant to …

Modeling the early events of severe acute respiratory syndrome coronavirus infection in vitro

YT Yen, F Liao, CH Hsiao, CL Kao, YC Chen… - Journal of …, 2006 - Am Soc Microbiol
The clinical picture of severe acute respiratory syndrome (SARS) is characterized by
pulmonary inflammation and respiratory failure, resembling that of acute respiratory distress …

[HTML][HTML] Toll-like receptors, chemokine receptors and death receptor ligands responses in SARS coronavirus infected human monocyte derived dendritic cells

HKW Law, CY Cheung, SF Sia, YO Chan, JSM Peiris… - BMC immunology, 2009 - Springer
Background The SARS outbreak in 2003 provides a unique opportunity for the study of
human responses to a novel virus. We have previously reported that dendritic cells (DCs) …

[HTML][HTML] Inhibition of cytokine gene expression and induction of chemokine genes in non-lymphatic cells infected with SARS coronavirus

M Spiegel, F Weber - Virology Journal, 2006 - Springer
Abstract Background SARS coronavirus (SARS-CoV) is the etiologic agent of the severe
acute respiratory syndrome. SARS-CoV mainly infects tissues of non-lymphatic origin, and …

Cytokine regulation in SARS coronavirus infection compared to other respiratory virus infections

T Okabayashi, H Kariwa, S Yokota, S Iki… - Journal of medical …, 2006 - Wiley Online Library
The pathogenesis of severe acute respiratory syndrome (SARS) is poorly understood and
cytokine dysregulation has been suggested as one relevant mechanism to be explored. We …

T cell responses to whole SARS coronavirus in humans

CK Li, H Wu, H Yan, S Ma, L Wang… - The Journal of …, 2008 - journals.aai.org
Effective vaccines should confer long-term protection against future outbreaks of severe
acute respiratory syndrome (SARS) caused by a novel zoonotic coronavirus (SARS-CoV) …