Long non-coding RNAs: potential new biomarkers for predicting tumor invasion and metastasis

C Jiang, X Li, H Zhao, H Liu - Molecular cancer, 2016 - Springer
Long non-coding RNAs (lncRNAs) play important roles in malignant neoplasia. Indeed,
many hallmarks of cancer define that the malignant phenotype of tumor cells are controlled …

Long noncoding RNA: an emerging paradigm of cancer research

MT Qiu, JW Hu, R Yin, L Xu - Tumor Biology, 2013 - Springer
Recent studies have demonstrated the importance of non-protein coding part of human
genome in carcinogenesis and metastasis. Among numerous kinds of non-protein coding …

Long non-coding RNAs in metastasis

Q Huang, J Yan, R Agami - Cancer and Metastasis Reviews, 2018 - Springer
Long non-coding RNA (lncRNA) genes have recently been discovered as key regulators of
developmental, physiological, and pathological processes in humans. Recent studies …

Long noncoding RNAs as new architects in cancer epigenetics, prognostic biomarkers, and potential therapeutic targets

D Meseure, K Drak Alsibai, A Nicolas… - BioMed research …, 2015 - Wiley Online Library
Recent advances in genome‐wide analysis have revealed that 66% of the genome is
actively transcribed into noncoding RNAs (ncRNAs) while less than 2% of the sequences …

Keep your eyes peeled for long noncoding RNAs: Explaining their boundless role in cancer metastasis, drug resistance, and clinical application

GK Barik, O Sahay, A Behera, D Naik… - Biochimica et Biophysica …, 2021 - Elsevier
Cancer metastasis and drug resistance are two major obstacles in the treatment of cancer
and therefore, the leading cause of cancer-associated mortalities worldwide. Hence, an in …

Long noncoding RNAs biomarker‐based cancer assessment

M Sarfi, M Abbastabar, E Khalili - Journal of cellular physiology, 2019 - Wiley Online Library
Cancer diagnosis have mainly relied on the incorporation of molecular biomarkers as part of
routine diagnostic tool. The molecular alteration ranges from those involving DNA, RNA …

[HTML][HTML] Long non-coding RNA in cancer

N Hauptman, D Glavač - International journal of molecular sciences, 2013 - mdpi.com
Long non-coding RNAs (lncRNAs) are pervasively transcribed in the genome and are
emerging as new players in tumorigenesis due to their various functions in transcriptional …

[HTML][HTML] Long non-coding RNAs in cancer invasion and metastasis

X Shen, P Qi, X Du - Modern Pathology, 2015 - Elsevier
Recent large-scale transcriptome analyses have revealed that the human genome contains
more than just protein-coding genes. Indeed, a large number of transcripts, including long …

Long non-coding RNAs as epigenetic regulators in cancer

A Vafadar, Z Shabaninejad… - Current …, 2019 - ingentaconnect.com
Long noncoding RNAs (lncRNAs) constitute large portions of the mammalian transcriptome
which appeared as a fundamental player, regulating various cellular mechanisms. LncRNAs …

Insight into the role of long noncoding RNA in cancer development and progression

CH Li, Y Chen - International review of cell and molecular biology, 2016 - Elsevier
Long noncoding RNA (LncRNA) is a large class of RNA molecules with size larger than 200
nucleotides. They exhibit cellular functions although having no protein-coding capability …