Aging and aging related neurodegenerative disease models and drug screening based on Caenorhabditis elegans: research progress

X Xue, J Zhang, S Song, Z LI… - Chinese Journal of …, 2017 - pesquisa.bvsalud.org
Caenorhabditis elegans is a very important model organism in life sciences. C. elegans has
been widely used in research on life sciences, especially in drug screening and the …

Aging and aging related neurodegenerative disease models and drug screening based on Caenorhabditis elegans: research progress.

XXL Xue XiaoLi, ZJQ Zhang JianQin… - 2017 - cabidigitallibrary.org
Caenorhabditis elegans is a very important model organism in life sciences. C. elegans has
been widely used in research on life sciences, especially in drug screening and the …

Caenorhabditis elegans in Chinese Medicinal Studies: Making the Case for Aging and Neurodegeneration

Q Wang, F Yang, W Guo, J Zhang, L Xiao… - Rejuvenation …, 2014 - liebertpub.com
Aging is a progressive process with degenerative changes of various tissues and organs. As
a classic model organism in genetics and neurobiology, Caenorhabditis elegans is also a …

Caenorhabditis elegans in Chinese medicinal studies: making the case for aging and neurodegeneration.

WQQ Wang QiangQiang, YF Yang Fan, GW Guo Wei… - 2014 - cabidigitallibrary.org
Aging is a progressive process with degenerative changes of various tissues and organs. As
a classic model organism in genetics and neurobiology, Caenorhabditis elegans is also a …

Aging-Related Neurodegenerative Diseases in Caenorhabditis elegans

DK Kim, SJ Lee - Aging Mechanisms: Longevity, Metabolism, and Brain …, 2015 - Springer
Neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease, are
aging-dependent. As aged population grows, neurodegenerative diseases have become …

Caenorhabditis elegans: A transgenic model for studying age-associated neurodegenerative diseases

N Rani, MM Alam, A Jamal, OB Ghaffar… - Ageing Research Reviews, 2023 - Elsevier
Neurodegenerative diseases (NDs) are a heterogeneous group of aging-associated
ailments characterized by interrupting cellular proteostasic machinery and the misfolding of …

Caenorhabditis elegans as a Useful Model for Studying Aging Mutations

S Zhang, F Li, T Zhou, G Wang, Z Li - Frontiers in endocrinology, 2020 - frontiersin.org
The Caenorhabditis elegans genome possesses homologs of about two-thirds of all human
disease genes. Based on its physiological aging characteristics and superiority, the use of …

Study on aging animal models and its application in activity screening of anti-aging drugs

YZ ZHOU - Chinese Traditional and Herbal Drugs, 2017 - pesquisa.bvsalud.org
Aging and aging-related diseases make human life burden increase year by year. We can
solve this problem by delaying aging and reducing the incidence of aging-related diseases …

Caenorhabditis elegans as a toolkit for studying mammalian aging pathways.

VS Virendra Shukla, SS Sangeeta Saxena… - 2016 - cabidigitallibrary.org
During the last few decades the free living soil nematode Caenorhabditis elegans has been
highlighted as an important model organism to decipher the role of several conserved …

Caenorhabditis elegans as a model organism for aging: relevance, limitations and future

R Litke, E Boulanger, C Fradin - Medecine Sciences: M/S, 2018 - europepmc.org
Aging is a physiological and complex process associated with increasing age of living
organisms. Simple model organisms have brought significant advances in our …