Multiple mechanisms are involved in kidney damage, among which the role of epigenetic
modifications in the occurrence and development of kidney diseases is constantly being …

Abstract N 6-methyladenosine (m6A) modification is a kind of RNA modification in which
methylation occurs at the sixth N position in adenosine in RNA, which can occur in various …

Abstract The N6-methyladenosine (m6A) modification is regulated by methylases, commonly
referred to as “writers,” and demethylases, known as “erasers,” leading to a dynamic and …

Chemical modifications are a specific and efficient way to regulate the function of biological
macromolecules. Among them, RNA molecules exhibit a variety of modifications that play …

Epigenetic modifications have received increasing attention and have been shown to be
extensively involved in kidney development and disease progression. Among them, the …

Aim: To identify the alterations of N6-methyladenosine (m6A) RNA profiles in cisplatin-
induced acute kidney injury (Cis-AKI) in mice. Materials and Methods: The total level of m6A …

Background N6-methyladenosine (m6A) is the most abundant modification known in
mRNAs. It participates in a variety of physiological and pathological processes, such as …

Aim: To reveal the alterations of N6-methyladenosine (m6A) epitranscriptome profile in
kidney after unilateral ureteral obstruction in mice. Materials & methods: Total renal m6A and …

Background Accumulating evidence has demonstrated that N6-methyladenosine (m 6 A)
plays important roles in a variety of diseases. However, the specific functions of m 6 A in …

Abstract N6-Methyladenosine (m6A) is the most prevalent internal modification of
messenger RNA (mRNA) in eukaryotes. The underlying molecular mechanisms of m6A …