Rationale and Design of a Large-Scale Trial Using Atrial Natriuretic Peptide (ANP) as an Adjunct to Percutaneous Coronary Intervention for ST-Segment Elevation …

M Asakura, K Jiyoong, T Minamino, Y Shintani… - Circulation …, 2004 - jstage.jst.go.jp
Background The benefits of percutaneous coronary intervention (PCI) in acute myocardial
infarction (AMI) are limited by reperfusion injury. In animal models, atrial natriuretic peptide …

Effect of atrial natriuretic peptide on left ventricular remodelling in patients with acute myocardial infarction

S Kasama, M Furuya, T Toyama… - European Heart …, 2008 - academic.oup.com
Atrial natriuretic peptide (ANP) is a member of the natriuretic peptide family that exerts
various biological effects via acting on the receptor-guanylyl cyclase system, increasing the …

Atrial natriuretic peptide therapy and in-hospital mortality in acute myocardial infarction patients undergoing percutaneous coronary intervention

T Isogai, H Matsui, H Tanaka, K Fushimi… - International Journal of …, 2016 - Elsevier
Background Atrial natriuretic peptide (ANP) therapy has been reported to have beneficial
effects in patients with acute myocardial infarction (AMI); however, its impact on in-hospital …

Natriuretic Peptides as an Adjunctive Treatment for Acute Myocardial Infarction Insights from the Meta-analysis of 1,389 Patients from 20 Trials

T Lyu, Y Zhao, T Zhang, W Zhou, F Yang… - International heart …, 2014 - jstage.jst.go.jp
Animal studies have reported a cardioprotective effect for atrial natriuretic peptide (ANP) or
brain natriuretic peptide (BNP) administration in the setting of acute myocardial infarction …

Administration of atrial natriuretic peptide attenuates reperfusion phenomena and preserves left ventricular regional wall motion after direct coronary angioplasty for …

H Kuga, K Ogawa, A Oida, I Taguchi… - Circulation …, 2003 - jstage.jst.go.jp
To evaluate the effects of synthetic human atrial natriuretic peptide (hANP) on myocardial
reperfusion injury and left ventricular remodeling, 19 patients within 12h of a first attack of …

Human atrial natriuretic peptide and nicorandil as adjuncts to reperfusion treatment for acute myocardial infarction (J-WIND): two randomised trials

M Kitakaze, M Asakura, J Kim, Y Shintani, H Asanuma… - The Lancet, 2007 - thelancet.com
Background Patients who have acute myocardial infarction remain at major risk of
cardiovascular events. We aimed to assess the effects of either human atrial natriuretic …

Intravenous atrial natriuretic peptide prevents left ventricular remodeling in patients with first anterior acute myocardial infarction

M Hayashi, T Tsutamoto, A Wada, K Maeda… - Journal of the American …, 2001 - jacc.org
OBJECTIVES The study evaluates the effect of atrial natriuretic peptide (ANP) compared
with nitroglycerin (GTN) on left ventricular (LV) remodeling after first anterior acute …

Atrial natriuretic peptide administered just prior to reperfusion limits infarction in rabbit hearts

XM Yang, S Philipp, JM Downey, MV Cohen - Basic research in cardiology, 2006 - Springer
We investigated whether atrial natriuretic peptide (ANP) given just prior to reperfusion
reduces infarction in rabbit hearts and whether protection is related to activation of protein …

Atrial natriuretic peptide increases inflammation, infarct size, and mortality after experimental coronary occlusion

AK Houng, RA McNamee, A Kerner… - American Journal …, 2009 - journals.physiology.org
Acute coronary artery occlusion triggers the release of atrial natriuretic peptide (ANP) from
the heart. ANP affects vasodilation, natriuresis, and inflammation, but the integrated …

Preischemic infusion of alpha-human atrial natriuretic peptide elicits myoprotection through a nitric oxide-dependent mechanism

H Okawa, H Horimoto, S Mieno, Y Nomura… - Journal of …, 2002 - europepmc.org
Objectives Alpha-human atrial natriuretic peptide (alpha-hANP) has been used to treat
patients with heart failure due to its natriuretic and vasodilatory activities. Recent reports …