Review on therapeutic targets for COVID-19: insights from cytokine storm

ML de Mélo Silva Júnior, LMA de Souza… - Postgraduate …, 2021 - academic.oup.com
Introduction Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been
caused the greatest pandemic of our century. Many of the deaths related to it are due to a …

A brief overview of SARS-CoV-2 infection and its management strategies: a recent update

A Das, S Pathak, M Premkumar… - Molecular and Cellular …, 2023 - Springer
The COVID-19 pandemic has become a global health crisis, inflicting substantial morbidity
and mortality worldwide. A diverse range of symptoms, including fever, cough, dyspnea, and …

Storm at the time of corona: a glimpse at the current understanding and therapeutic opportunities of the SARS-CoV-2 cytokine storm

M Torabi-Rahvar, N Rezaei - Current Pharmaceutical Design, 2021 - ingentaconnect.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may lead to severe
disease in some cases, leading to acute respiratory distress syndrome, multi-organ failure …

Tackling the cytokine storm in COVID-19, challenges and hopes

SM Abdin, SM Elgendy, SK Alyammahi, DW Alhamad… - Life Sciences, 2020 - Elsevier
The outbreak of Coronavirus disease 2019 (COVID-19) is the current world health concern,
presenting a public health dilemma with ascending morbidity and mortality rates exceeding …

[HTML][HTML] Calming the inflammatory storm in severe COVID-19 infections: Role of biologics-A narrative review

D Banji, SS Alqahtani, OJF Banji… - Saudi Pharmaceutical …, 2021 - Elsevier
The risk of Coronavirus infection continues, and the fear of resurgence indicates the lack of a
successful therapeutic strategy. In severe COVID-19 infection, many immune cells and their …

[HTML][HTML] Immune system response during viral Infections: Immunomodulators, cytokine storm (CS) and Immunotherapeutics in COVID-19

FH Pottoo, T Abu-Izneid, AM Ibrahim, MN Javed… - Saudi pharmaceutical …, 2021 - Elsevier
Coronaviruses are non-segmented and single stranded positive-sense RNA (+ ssRNA)
viruses. To date, 06 human coronaviruses (HCoVs) are reported; α-CoVs (HCoVs-NL63 and …

Coronavirus disease 2019: investigational therapies in the prevention and treatment of hyperinflammation

I Amigues, AH Pearlman, A Patel, P Reid… - Expert review of …, 2020 - Taylor & Francis
Introduction: The mortality of coronavirus disease 2019 (COVID-19) is frequently driven by
an injurious immune response characterized by the development of acute respiratory …

COVID-19 as an acute inflammatory disease

RH Manjili, M Zarei, M Habibi… - The journal of immunology, 2020 - journals.aai.org
Abstract The 2019 coronavirus disease (COVID-19) pandemic caused by the virus severe
acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has created an unprecedented …

The cytokine storm in COVID-19: the strongest link to morbidity and mortality in the current epidemic

M Basheer, E Saad, N Assy - COVID, 2022 - mdpi.com
COVID-19 is an infectious disease caused by the SARS-CoV-2 virus. The clinical
presentations of the SARS-CoV-2 infection are widely variable and treatment strategies for …

[HTML][HTML] Recent advances in management of COVID-19: A review

S Mouffak, Q Shubbar, E Saleh, R El-Awady - Biomedicine & …, 2021 - Elsevier
Abstract The coronavirus disease 2019 (COVID-19) pandemic caused and is still causing
significant mortality and economic consequences all over the globe. As of today, there are …