SARS-CoV-2 mediated lung inflammatory responses in host: targeting the cytokine storm for therapeutic interventions

P Asrani, MI Hassan - Molecular and Cellular Biochemistry, 2021 - Springer
The recent exposure of novel coronavirus strain, severe acute respiratory syndrome (SARS-
CoV-2) has spread to different countries at an alarming rate. Faster transmission rate and …

Targeting inflammation and cytokine storm in COVID-19

Q Huang, X Wu, X Zheng, S Luo, S Xu… - Pharmacological Research, 2020 - Elsevier
The ongoing pandemic of coronavirus disease 2019 (COVID-19), caused by the severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused over 9.2 million …

A review of treatment of coronavirus disease 2019 (COVID-19): Therapeutic repurposing and unmet clinical needs

PL Chen, NY Lee, CT Cia, WC Ko… - Frontiers in …, 2020 - frontiersin.org
For the initial phase of pandemic of coronavirus disease 2019 (COVID-19), repurposing
drugs that in vitro inhibit severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) …

Pathophysiology of acute respiratory syndrome coronavirus 2 infection: a systematic literature review to inform EULAR points to consider

A Najm, A Alunno, X Mariette, B Terrier, G De Marco… - RMD open, 2021 - rmdopen.bmj.com
Background The SARS-CoV-2 pandemic is a global health problem. Beside the specific
pathogenic effect of SARS-CoV-2, incompletely understood deleterious and aberrant host …

[PDF][PDF] Therapeutic options for COVID-19: a review

R Pujari, MV Thommana, BR Mercedes, A Serwat - Cureus, 2020 - cureus.com
An acute respiratory disease caused by a novel coronavirus [severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), previously known as 2019-nCoV], the coronavirus …

The interplay between inflammatory pathways and COVID-19: A critical review on pathogenesis and therapeutic options

S Choudhary, K Sharma, O Silakari - Microbial pathogenesis, 2021 - Elsevier
Abstract COVID-19, caused by SARS-CoV-2, emerged as the deadliest outbreak that has
now become a serious health issue to mankind. Activation of inflammatory signaling …

COVID-19 infection: an overview on cytokine storm and related interventions

S Montazersaheb, SM Hosseiniyan Khatibi, MS Hejazi… - Virology journal, 2022 - Springer
Abstract Coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory
syndrome coronavirus-2 (SARS-CoV-2) has posed a significant threat to global health. This …

Potential therapeutic options for COVID-19: current status, challenges, and future perspectives

C Sarkar, M Mondal, M Torequl Islam… - Frontiers in …, 2020 - frontiersin.org
The COVID-19 pandemic represents an unprecedented challenge for the researchers to
offer safe, tolerable, and effective treatment strategies for its causative agent known as …

Current treatments and therapeutic options for COVID-19 patients: a systematic review

E Mehraeen, Z Najafi, B Hayati… - … Current Drug Targets …, 2022 - ingentaconnect.com
Introduction: COVID-19 is the third rising epidemic in the 21st century that quickly turned into
a worldwide pandemic. Many clinical studies have been achieved to investigate treatments …

[HTML][HTML] SARS-Cov-2 infection: Response of human immune system and possible implications for the rapid test and treatment

G di Mauro, C Scavone, C Rafaniello, F Rossi… - International …, 2020 - Elsevier
The new coronavirus outbreak is an ongoing pandemic that is caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). The new coronavirus SARS-Cov-2 …