S100B causes apoptosis in a myoblast cell line in a RAGE‐independent manner

G Sorci, F Riuzzi, AL Agneletti… - Journal of cellular …, 2004 - Wiley Online Library
Abstract S100B, a Ca2+‐modulated protein with both intracellular and extracellular
regulatory roles, is most abundant in astrocytes, is expressed in various amounts in several …

S100-mediated signal transduction in the nervous system and neurological diseases.

DB Zimmer, J Chaplin, A Baldwin… - Cellular and molecular …, 2005 - europepmc.org
This article presents new information regarding the complement/level of S100 family
members expressed in the brain and reviews the contribution of brain S100 family members …

S100B inhibits myogenic differentiation and myotube formation in a RAGE-independent manner

G Sorci, F Riuzzi, AL Agneletti, C Marchetti… - Molecular and cellular …, 2003 - Taylor & Francis
S100B is a Ca2+-modulated protein of the EF-hand type with both intracellular and
extracellular roles. S100B, which is most abundant in the brain, has been shown to exert …

S100B protein stimulates microglia migration via RAGE-dependent up-regulation of chemokine expression and release

R Bianchi, E Kastrisianaki, I Giambanco… - Journal of Biological …, 2011 - ASBMB
The Ca 2+-binding protein of the EF-hand type, S100B, is abundantly expressed in and
secreted by astrocytes, and release of S100B from damaged astrocytes occurs during the …

S100B stimulates myoblast proliferation and inhibits myoblast differentiation by independently stimulating ERK1/2 and inhibiting p38 MAPK

F Riuzzi, G Sorci, R Donato - Journal of cellular physiology, 2006 - Wiley Online Library
The Ca2þ-modulated protein of the EF-hand type, S100B, was shown to inhibit rat L6
myoblast differentiation and myotube formation by interacting with a high affinity with an …

[HTML][HTML] S100B's double life: intracellular regulator and extracellular signal

R Donato, G Sorci, F Riuzzi, C Arcuri, R Bianchi… - … et Biophysica Acta (BBA …, 2009 - Elsevier
The Ca2+-binding protein of the EF-hand type, S100B, exerts both intracellular and
extracellular functions. Recent studies have provided more detailed information concerning …

S100: a multigenic family of calcium-modulated proteins of the EF-hand type with intracellular and extracellular functional roles

R Donato - The international journal of biochemistry & cell biology, 2001 - Elsevier
S100 is a multigenic family of non-ubiquitous Ca2+-modulated proteins of the EF-hand type
expressed in vertebrates exclusively and implicated in intracellular and extracellular …

[HTML][HTML] S100B in myoblasts regulates the transition from activation to quiescence and from quiescence to activation and reduces apoptosis

C Tubaro, C Arcuri, I Giambanco, R Donato - Biochimica et Biophysica Acta …, 2011 - Elsevier
S100B protein activates IKKβ/NF-κB within myoblasts, thereby inhibiting the expression of
MyoD and the MyoD-downstream effectors, myogenin and p21WAF1, and myoblast …

S100B and S100A6 differentially modulate cell survival by interacting with distinct RAGE (receptor for advanced glycation end products) immunoglobulin domains

E Leclerc, G Fritz, M Weibel, CW Heizmann… - Journal of Biological …, 2007 - ASBMB
S100 proteins are EF-hand calcium-binding proteins with various intracellular functions
including cell proliferation, differentiation, migration, and apoptosis. Some S100 proteins are …

S100β induces apoptotic cell death in cultured astrocytes via a nitric oxide-dependent pathway

J Hu, LJ Van Eldik - Biochimica et Biophysica Acta (BBA)-Molecular Cell …, 1996 - Elsevier
S100β is a calcium binding protein expressed primarily by astrocytes in the brain. In
initiating studies of the toxic signalling pathways activated by high concentrations of S100β …