Resolution of the Facilitated Transport of Dehydroascorbic Acid from Its Intracellular Accumulation as Ascorbic Acid (∗)

JC Vera, CI Rivas, FV Velásquez, RH Zhang… - Journal of Biological …, 1995 - ASBMB
We performed a detailed kinetic analysis of the uptake of dehydroascorbic acid by HL-60
cells under experimental conditions that enabled the differentiation of dehydroascorbic acid …

The glucose transporter-2 (GLUT2) is a low affinity dehydroascorbic acid transporter

L Mardones, V Ormazabal, X Romo, C Jaña… - Biochemical and …, 2011 - Elsevier
We studied the acquisition of dehydroascorbic acid by rat hepatocytes, H4IIE rat hepatoma
cells and Xenopus laevis oocytes. Transport kinetics and competition and inhibition studies …

Glucose transporter isoforms GLUT1 and GLUT3 transport dehydroascorbic acid

SC Rumsey, O Kwon, GW Xu, CF Burant… - Journal of Biological …, 1997 - ASBMB
Dehydroascorbic acid (DHA) is rapidly taken up by cells and reduced to ascorbic acid (AA).
Using the Xenopus laevis oocyte expression system we examined transport of DHA and AA …

Glucose-independent transport of dehydroascorbic acid in human erythrocytes

J Bianchi, RC Rose - … of the Society for Experimental Biology …, 1986 - journals.sagepub.com
It has been previously reported that glucose and its structural analogs inhibit
dehydroascorbic acid (DHA) transport across the membranes of nonpolar cells, which led to …

Ascorbic acid accumulation and transport in human fibroblasts

RW Welch, P Bergsten, JD Butler… - Biochemical …, 1993 - portlandpress.com
As the initial step in the use of fibroblasts as a model system for 'in situ kinetics', ascorbic
acid (vitamin C) accumulation in normal human fibroblasts was investigated for the first time …

Accumulation of vitamin C (ascorbate) and its oxidized metabolite dehydroascorbic acid occurs by separate mechanisms

RW Welch, Y Wang, A Crossman, JB Park… - Journal of Biological …, 1995 - ASBMB
It is unknown whether ascorbate alone (vitamin C), its oxidized metabolite dehydroascorbic
acid alone, or both species are transported into human cells. This problem was addressed …

The membrane transport of ascorbic acid.

GV Mann, P Newton - Annals of the New York Academy of Sciences, 1975 - europepmc.org
A system for measuring the rate of transport of dehydroascorbate into human red blood cells
shows Michaelis-Menten type kinetics with substrate inhibition at levels above 150 muM …

[引用][C] Uptake of ascorbic acid by leukocytes

U Moser - Annals of the New York Academy of Sciences, 1987 - Wiley Online Library
Ascorbic acid (AA) is accumulated by various tissues such as adrenal glands, pituitary
gland, eye lens, as well as by leukocytes (TABLE l).','In order to achieve a concentration of …

Specificity of ascorbate analogs for ascorbate transport: synthesis and detection of [125I] 6-deoxy-6-iodo-l-ascorbic acid and characterization of its ascorbate-specific …

SC Rumsey, RW Welch, HM Garraffo, P Ge… - Journal of Biological …, 1999 - ASBMB
Cellular ascorbic acid accumulation occursin vitro by two distinct mechanisms: transport of
ascorbate itself or transport and subsequent intracellular reduction of its oxidized product …

Dehydroascorbic acid transport by GLUT4 in XenopusOocytes and isolated rat adipocytes

SC Rumsey, R Daruwala, H Al-Hasani… - Journal of Biological …, 2000 - ASBMB
Dehydroascorbic acid (DHA), the first stable oxidation product of vitamin C, was transported
by GLUT1 and GLUT3 inXenopus laevis oocytes with transport rates similar to that of 2 …