Splicing of nuclear precursor messenger RNAs is an important and ubiquitous type of gene
regulation in metazoans. Splicing joins the coding sequences called exons by removing the …

Splicing of precursor mRNAs (pre-mRNA) is an important step during eukaryotic gene
expression. The identification of the actual splice sites and the proper removal of introns are …

The splicing of pre‐mRNAs is an essential step of gene expression in eukaryotes. Introns
are removed from split genes through the activities of the spliceosome, a large ribonuclear …

One of the fundamental issues in RNA splicing research is represented by understanding
how the spliceosome can successfully define exons and introns in a huge variety of pre …

The protein-coding regions of most vertebrate genes are split, giving rise to primary
transcripts containing introns and exons; the latter must be spliced in the nucleus to form the …

Most messenger RNAs in higher eukaryotes are transcribed as precursors containing
intervening sequences (introns). Introns are removed by a sophisticated processing …

Advances over the past year have provided new insights into the mechanisms involved in
the initial recognition and pairing of the 5′ and 3′ splice sites in complex metazoan pre …

One of the most surprising discoveries of molecular biology was the realization that
eukaryotic messenger RNAs (mRNA) are usually transcribed as precursors containing …

Alternative splicing is a widespread means of increasing protein diversity and regulating
gene expression in eukaryotes. Much progress has been made in understanding the …

Pre-mRNA splicing involves removing non-coding introns from RNA transcripts. It is carried
out by the spliceosome, along with other auxiliary factors. In general, research in splicing …