Recent advances in the pathophysiologic understanding of the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infection has indicated that patients with severe …

Cytokine signaling, especially interferon (IFN) signaling is closely linked to several aspects
of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection. During initial …

The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
caused the unprecedented COVID-19 pandemic, which has infected over 178 million people …

As the incidence of COVID-19 increases with time, more and more efforts are made to pave
a way out for the therapeutic strategies to deal with the disease progression. Inflammation …

HiJAKing SARS-CoV-2? The potential role of JAK inhibitors in the management of COVID-19 |
Science Immunology news careers commentary Journals Science Science brought to you …

Background Currently, JAK-inhibitors are repurposed for therapy of Covid-19 because of
their ability in restraining immune response, yet the corroboration regarding their advantage …

ABSTRACT SARS-CoV-2 can infect multiple organs, including lung, intestine, kidney, heart,
liver, and brain. The molecular details of how the virus navigates through diverse cellular …

Background: Cytokine storm observed in severe Coronavirus Disease 2019 (COVID-19)
patients contributes to poor clinical outcomes and increased mortality. We aim to conduct a …

In December 2019, a novel coronavirus pneumonia (COVID-19) caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) suddenly broke out in China and rapidly …

Cytokine release syndrome (CRS) may be the key factor in the pathology of severe
coronavirus disease 2019 (COVID-19). As a major driver in triggering CRS in patients with …