A better understanding of the molecular and cellular determinants that influence the
pathology of Parkinson's disease (PD) is essential for developing effective diagnostic …

The aggregation of alpha synuclein (α‐syn) is a neuropathological feature that defines a
spectrum of disorders collectively termed synucleinopathies, and of these, Parkinson's …

The discovery that alpha-synuclein (α-syn) is the primary component of the
neuropathological hallmarks of Parkinson's disease (PD) and the identification of α-syn …

α-Synuclein (α-syn), a small highly conserved presynaptic protein containing 140 amino
acids, is thought to be the main pathological hallmark in related neurodegenerative …

Several lines of evidence suggest that phosphorylation of α-synuclein (α-syn) at S87 or
S129 may play an important role in regulating its aggregation, fibrillogenesis, Lewy body …

Over the last two decades, many experimental and clinical studies have provided solid
evidence that alpha-synuclein (α-syn), a small, natively unfolded protein, is closely related to …

Disorders characterized by α-synuclein (α-syn) accumulation, Lewy body formation and
parkinsonism (and in some cases dementia) are collectively known as Lewy body diseases …

α-Synuclein (αsyn) is an abundant brain neuronal protein that can misfold and polymerize to
form toxic fibrils coalescing into pathologic inclusions in neurodegenerative diseases …

Parkinson's disease is the most common neurodegenerative movement disorder. The motor
impairments of Parkinson's disease are caused by the loss of dopaminergic neurons in the …

The aggregation of alpha-synuclein (α-Syn) plays a critical role in the development of
Parkinson's disease (PD) and other synucleinopathies. α-Syn, which is encoded by the …