Alzheimer's Disease (AD) is characterized by the accumulation of extracellular amyloid-β
(Aβ) as well as CNS and systemic inflammation. Microglia, the myeloid cells resident in the …

Microglia are the innate immune cells of the central nervous system that adopt rapid
functional changes in response to Damage Associated Molecular Patterns, including …

MicroRNAs (miRNAs) have emerged as a class of small, endogenous, regulatory RNAs that
exhibit the ability to epigenetically modulate the translation of mRNAs into proteins. This …

MicroRNAs are recognized as important regulators of many facets of physiological brain
function while also being implicated in the pathogenesis of several neurological disorders …

Inflammation is a common component of acute injuries of the central nervous system (CNS)
such as ischemia, and degenerative disorders such as Alzheimer's disease. Glial cells play …

Microglia play a critical role in brain homeostasis and disease progression. In
neurodegenerative conditions, microglia acquire the neurodegenerative phenotype (MGnD) …

Background: Neuroinflammation has important effects on cognitive functions in the
pathophysiological process of Alzheimer's Disease (AD). In the current report, we …

MicroRNAs (miRNAs) are a family of small non-coding RNAs (∼ 22 nucleotides) that fine-
tune protein expression by either silencing mRNA translation or directly targeting gene …

MicroRNAs (miRNAs) are small regulatory RNAs that participate in posttranscriptional gene
regulation in a sequence-specific manner. However, little is understood about the role (s) of …

MicroRNAs (miRNAs) are small noncoding RNA molecules, with essential functions in RNA
silencing and post-transcriptional regulation of gene expression. miRNAs appear to regulate …