NF-κB comprises a family of five transcription factors that form distinct protein complexes, which bind to consensus DNA sequences at promoter regions of responsive genes …
Abundant data support a key role for the transcription factor nuclear factor-κB (NF-κB) signaling pathway in controlling the initiation and progression of human cancer. NF-κB and …
CH Lee, YT Jeon, SH Kim, YS Song - Biofactors, 2007 - Wiley Online Library
Nuclear factor κB (NF‐κB), a transcription factor, plays an important role in carcinogenesis as well as in the regulation of immune and inflammatory responses. NF‐κB induces the …
C Mauro, F Zazzeroni, S Papa, C Bubici… - Inflammation and Cancer …, 2009 - Springer
NF-κB transcription factors marshal innate and adaptive immunity and inflammation. NF-κB also counters programmed cell death (PCD) induced by the proinflammatory cytokine tumor …
L Vermeulen, W Vanden Berghe… - The Link Between …, 2006 - Springer
Nuclear factor κB (NF-κB) is regarded as a key regulator of inflammation; hence, several inflammatory diseases result from deregulation of NF-κB signaling. There is, however, also …
YR Puar, MK Shanmugam, L Fan, F Arfuso, G Sethi… - Biomedicines, 2018 - mdpi.com
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is responsible for the regulation of a large number of genes that are involved in important physiological …
NF-κB pathway exerts an essential function in the regulation of the immune response, which has been the nucleus of numerous studies for the past 25 years. Both activation of the …
G Xiao, J Fu - American journal of cancer research, 2011 - ncbi.nlm.nih.gov
Recent studies have clearly linked nuclear factor-kappaB (NF-κB), a transcription factor that plays a central role in regulating immune and inflammatory responses, to tumor …
M Karin - … Carcinogenesis: Published in cooperation with the …, 2006 - Wiley Online Library
In addition to being a central coordinator of immune responses, NF‐κB signaling also plays a critical role in cancer development and progression and it may determine the response to …