ipso-Annulation represents an attractive approach to synthesize a variety of spirocyclic
compounds having a quaternary carbon center. Furthermore, these compounds also serve …

An efficient synthetic approach has been developed for the construction of the
spirocyclopentanone skeleton via a phosphine‐catalyzed [3+ 2] annulation reaction. With …

A new, general method for the synthesis of spiro [4, 5] trienones is described by the
intramolecular ipso-halocyclization of 4-(p-unsubstituted-aryl)-1-alkynes. In the presence of …

Spirocyclopropane represents a privileged structural scaffold for accessing synthetic
libraries of densely functionalized spirocarbo-and heterocyclic compounds. Due to the …

A catalytic domino spirocyclization of 1, 7-enynes with simple cycloalkanes and cyclo-1, 3-
dicarbonyls has been established via multiple C–C bond formations from alkynyl/alkenyl …

New methods for the construction of highly substituted carbocycles with a defined
configuration are important for the synthesis of natural products and drugs.[1] The synthesis …

We report the convergent synthesis of bicyclo [3.1. 0] hexanes possessing an all-carbon
quaternary center via a (3+ 2) annulation of cyclopropenes with cyclopropylanilines. Using …

An unprecedented umpolung spirocyclopropanation reaction of p-quinone methides and α-
keto carbonyls is described. Our umpolung strategy based on 1, 6-conjugate addition and …

AP (NMe2) 3-mediated reductive cyclopropanation reaction of α-keto esters or amides with
isatin-derived alkenes has been developed, providing efficient and diastereoselective …

A novel DBU-mediated stereoselective spirocyclopropanation of para-quinone methides
with sulfonium salts has been developed on the basis of the mode involving a 1, 6-conjugate …