[HTML][HTML] Endothelial dysfunction and immunothrombosis as key pathogenic mechanisms in COVID-19

A Bonaventura, A Vecchié, L Dagna… - Nature Reviews …, 2021 - nature.com
Abstract Coronavirus disease 2019 (COVID-19) is a clinical syndrome caused by infection
with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Patients with severe …

[HTML][HTML] Pathophysiological mechanisms of thrombosis in acute and long COVID-19

H Jing, X Wu, M Xiang, L Liu, VA Novakovic… - Frontiers in …, 2022 - frontiersin.org
COVID-19 patients have a high incidence of thrombosis, and thromboembolic complications
are associated with severe COVID-19 and high mortality. COVID-19 disease is associated …

Coagulation disorders in COVID-19: role of toll-like receptors

I Biswas, GA Khan - Journal of Inflammation Research, 2020 - Taylor & Francis
Abstract Coronavirus disease 2019 (COVID-19) has spread rapidly throughout the world.
The range of the disease is broad but among hospitalized patients with COVID-19 are …

[HTML][HTML] Immunoinflammatory, thrombohaemostatic, and cardiovascular mechanisms in COVID-19

S Gencer, M Lacy, D Atzler… - Thrombosis and …, 2020 - thieme-connect.com
The global coronavirus disease 2019 (COVID-19) pandemic has deranged the recent
history of humankind, afflicting more than 27 million individuals to date. While the majority of …

Vascular neutrophilic inflammation and immunothrombosis distinguish severe COVID‐19 from influenza pneumonia

L Nicolai, A Leunig, S Brambs, R Kaiser… - … of Thrombosis and …, 2021 - Wiley Online Library
Objective Infection with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)
can lead to severe pneumonia, but also thrombotic complications and non‐pulmonary organ …

Immunothrombotic dysregulation in COVID-19 pneumonia is associated with respiratory failure and coagulopathy

L Nicolai, A Leunig, S Brambs, R Kaiser… - Circulation, 2020 - Am Heart Assoc
Background: Severe acute respiratory syndrome corona virus 2 infection causes severe
pneumonia (coronavirus disease 2019 [COVID-19]), but the mechanisms of subsequent …

COVID-19, immunothrombosis and venous thromboembolism: biological mechanisms

J Loo, DA Spittle, M Newnham - Thorax, 2021 - thorax.bmj.com
Thrombotic events that frequently occur in COVID-19 are predominantly venous
thromboemboli (VTE) and are associated with increasing disease severity and worse clinical …

[HTML][HTML] Coagulopathy, endothelial dysfunction, thrombotic microangiopathy and complement activation: potential role of complement system inhibition in COVID-19

X Wang, KK Sahu, J Cerny - Journal of thrombosis and thrombolysis, 2021 - Springer
Abstract Coronavirus disease-2019 (COVID-19) is a rapidly evolving health crisis caused by
the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). COVID-19 is a novel …

[HTML][HTML] Thrombocytopathy and endotheliopathy: crucial contributors to COVID-19 thromboinflammation

SX Gu, T Tyagi, K Jain, VW Gu, SH Lee… - Nature Reviews …, 2021 - nature.com
The core pathology of coronavirus disease 2019 (COVID-19) is infection of airway cells by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that results in excessive …

The emerging threat of (micro) thrombosis in COVID-19 and its therapeutic implications

JD McFadyen, H Stevens, K Peter - Circulation research, 2020 - Am Heart Assoc
The recent emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
and the ensuing global pandemic has presented a health emergency of unprecedented …