A cytokine circus with a viral ringleader: SARS-CoV-2-associated cytokine storm syndromes

SS Cabler, AR French, A Orvedahl - Trends in Molecular Medicine, 2020 - cell.com
An unbridled host immune response to severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) infection is likely to underlie severe cases of the disease and has been …

COVID-19 and cytokine storm syndrome: are there lessons from macrophage activation syndrome?

MJ Ombrello, GS Schulert - Translational Research, 2021 - Elsevier
Although interest in “cytokine storms” has surged over the past decade, it was massively
amplified in 2020 when it was suggested that a subset of patients with COVID-19 developed …

Cytokine storm syndrome in SARS-CoV-2: a review

B Wahid, N Rani, M Idrees - Zeitschrift für Naturforschung C, 2022 - degruyter.com
After wreaking havoc on a global level with a total of 5,488,825 confirmed cases and
349,095 deaths as of May 2020, severe acute respiratory syndrome coronavirus 2 is truly …

Cytokine storm syndrome in coronavirus disease 2019: A narrative review

YM Gao, G Xu, B Wang, BC Liu - Journal of internal medicine, 2021 - Wiley Online Library
Cytokine storm syndrome (CSS) is a critical clinical condition induced by a cascade of
cytokine activation, characterized by overwhelming systemic inflammation …

[PDF][PDF] Cytokine Storm syndrome in COVID-19 patients: Characteristics And diagnosis

RM Harfouch - Ann Clin Med Case Rep, 2021 - researchgate.net
Cytokine storm syndrome (CSS) is a critical condition induced by a cascade of cytokine
activation, characterized by overwhelming systemic inflammation, hyperferritinaemia …

Is severe COVID-19 a cytokine storm syndrome: a hyperinflammatory debate

P Mehta, DC Fajgenbaum - Current opinion in Rheumatology, 2021 - journals.lww.com
Hyperinflammation is a key component of severe COVID-19, residing underneath the
cytokine storm umbrella term, associated with poor outcomes. Better understanding of the …

COVID-19 cytokine storm syndrome: a threshold concept

LYC Chen, TTT Quach - The Lancet Microbe, 2021 - thelancet.com
The COVID-19 pandemic has placed the practice of medicine at a threshold overlooking a
new and different era, 1 and has led to the evolving concept of COVID-19 cytokine storm …

Cytokine storm in COVID-19:“when you come out of the storm, you won't be the same person who walked in”

V Castelli, A Cimini, C Ferri - Frontiers in immunology, 2020 - frontiersin.org
In December 2019, a novel coronavirus, COVID-19, was discovered to be the causal agent
of a severe respiratory infection named SARS-CoV-2, and it has since been recognized …

Cytokine and cytokine storm.

YL Wang, F Wang, J Geng - 2020 - cabidigitallibrary.org
Cytokines are a diverse group of small molecule proteins or peptides that are secreted by
cells for the purpose of intercellular delivery signaling and communication, which play an …

Cytokine storm syndrome in SARS-CoV-2 infections: a functional role of mast cells

B Hafezi, L Chan, JP Knapp, N Karimi, K Alizadeh… - Cells, 2021 - mdpi.com
Cytokine storm syndrome is a cascade of escalated immune responses disposing the
immune system to exhaustion, which might ultimately result in organ failure and fatal …